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Mallory–Weiss syndrome is a condition where high intra-abdominal pressures causes laceration and bleeding of the mucosa called Mallory-Weiss tears. [1] Additionally, Mallory–Weiss syndrome is one of the most common causes of acute upper gastrointestinal bleeding , counting of around 1-15% of all cases in adults and less than 5% in children.
George Kenneth Mallory (February 14, 1900 – April 8, 1986) was an American pathologist chiefly remembered for describing the Mallory–Weiss tear. He was born in Boston , Massachusetts on 14 February 1900, the son of Frank Burr Mallory .
[3] [4] A related condition is Mallory-Weiss syndrome which is only a mucosal tear. A common site of iatrogenic perforation is the cervical esophagus just above the upper sphincter, whereas spontaneous rupture as seen in Boerhaave syndrome perforation commonly occurs in the lower third of the esophagus. [5]
Abstinence: Stopping further alcohol consumption is the number one factor for recovery in patients with alcoholic hepatitis. [ 16 ] Nutrition Supplementation: Protein and calorie deficiencies are seen frequently in patients with alcoholic hepatitis, and it negatively affects their outcomes.
Micrograph showing a Mallory body with the characteristic twisted-rope appearance (centre of image - within a ballooning hepatocyte). H&E stain. In histopathology, a Mallory body, Mallory–Denk body (MDB), or Mallory's hyaline is an inclusion found in the cytoplasm of liver cells. [1] Mallory bodies are damaged intermediate filaments within ...
A randomized, double blind trial published in JAMA in 1994 [5] showed that management for alcohol withdrawal that was guided by the CIWA scale resulted in decreased treatment duration and total use of benzodiazepines. The goal of the CIWA scale is to provide an efficient and objective means of assessing alcohol withdrawal.
Each item is scored on a scale of 0 to 3, giving the evaluation a range of 0 to 45. A score of 1-9 is indicative of a low dependence on alcohol, a score of 10-19 is indicative of a moderate dependence on alcohol, and a score of 20 or greater is indicative of a high dependence on alcohol. [2]
The CAGE questionnaire, the name of which is an acronym of its four questions, is a widely used screening test for problem drinking and potential alcohol problems.The questionnaire takes less than one minute to administer, [1] and is often used in primary care or other general settings as a quick screening tool rather than as an in-depth interview for those who have alcoholism.