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Gout can present in several ways, although the most common is a recurrent attack of acute inflammatory arthritis (a red, tender, hot, swollen joint). [4] The metatarsophalangeal joint at the base of the big toe is affected most often, accounting for half of cases. [ 10 ]
Gout is a common form of inflammatory arthritis. It happens due to high levels of uric acid in the body. Researchers estimate that gout impacts one to four percent of people around the world.
Gout is inflammation caused by the deposition of needle-shaped monosodium urate crystals in the joints. It is the most common type of inflammatory arthritis in the United States. The disease typically affects a single joint in earlier stages but can progress into polyarthritis over time.
Unless high blood levels of uric acid are determined in a clinical laboratory, hyperuricemia may not cause noticeable symptoms in most people. [5] Development of gout – which is a painful, short-term disorder – is the most common consequence of hyperuricemia, which causes deposition of uric acid crystals usually in joints of the extremities, but may also induce formation of kidney stones ...
A centerpiece section contained a feature puzzle or puzzles, such as puzzles from the World Puzzle Championship or the annual Lt. Nodumbo puzzle mystery. Until the July 2009 issue it contained a contest in every issue, most often a variety crossword or trivia quiz, and the contest resumed upon the Games merger.
A puzzle is a game, problem, or toy that tests a person's ingenuity or knowledge. In a puzzle, the solver is expected to put pieces together ( or take them apart ) in a logical way, in order to find the solution of the puzzle.
An American-style 15×15 crossword grid layout. A crossword (or crossword puzzle) is a word game consisting of a grid of black and white squares, into which solvers enter words or phrases ("entries") crossing each other horizontally ("across") and vertically ("down") according to a set of clues.
Margaret Petherbridge Farrar (March 23, 1897 – June 11, 1984) was an American journalist and the first crossword puzzle editor for The New York Times (1942–1968). Creator of many of the rules of modern crossword design, she compiled and edited a long-running series of crossword puzzle books – including the first book of any kind that Simon & Schuster published (1924). [1]