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Criteria for diagnosis of Waldenström macroglobulinemia include: IgM monoclonal gammopathy that excludes chronic lymphocytic leukemia and mantle cell lymphoma. Evidence of anemia, constitutional symptoms, hyperviscosity, swollen lymph nodes, or enlargement of the liver and spleen that can be attributed to an underlying lymphoproliferative ...
Bing–Neel syndrome (BNS) is an extremely rare neurologic complication of Waldenström macroglobulinemia (WM), which is a chronic lymphoproliferative disorder. [1] There's no clear definition of BNS but what is known so far is that unlike WM, It involves the central nervous system (CNS), infiltrated by differentiated malignant B cells and by having hyperglobulinemia. [2]
In the study, 75.6% of patients with Waldenstrom's macroglobulinemia (WM) saw cancer decrease in size or disappear after treatment with Cellectar's therapy iopofosine.
The incidence of Waldenstrom’s macroglobulinemia ranges from 0.36 1, 2 to 0.57 3 per 100,000 people in the United States or approximately 1,200 to 1,900 annually. With a median disease duration approaching 10 years, 4 approximately 12,000 to 19,000 patients are living with Waldenstrom’s macroglobulinemia in the United States.
The condition was first described in 1909 by Danish ophthalmologist Christian Frederick Heerfordt, for whom the syndrome is now named. [6] It was originally attributed to mumps, but after further studies by Swedish doctor Jan G. Waldenström in 1937, it was classified as a distinct manifestation of sarcoidosis.
Turner announced, in a Dec. 11 interview with People, that he'd been diagnosed with an incurable form of bone marrow cancer called Waldenstrom macroglobulinemia. In an interview with People ...
Macroglobulinemia is the presence of increased levels of macroglobulins in the circulating blood.It is a plasma cell dyscrasia, resembling leukemia, with cells of lymphocytic, plasmacytic, or intermediate morphology, which secrete a monoclonal immunoglobulin M component.
Waldenstrom macroglobulinemia is considered a type of non-Hodgkin's lymphoma. It's sometimes called lymphoplasmacytic lymphoma." ... Speaking of the diagnosis, Nist said, "He told me, though, that ...