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Waldenström macroglobulinemia was first described by Jan G. Waldenström (1906–1996) in 1944 in two patients with bleeding from the nose and mouth, anemia, decreased levels of fibrinogen in the blood (hypofibrinogenemia), swollen lymph nodes, neoplastic plasma cells in bone marrow, and increased viscosity of the blood due to increased levels ...
The incidence of Waldenstrom’s macroglobulinemia ranges from 0.36 1, 2 to 0.57 3 per 100,000 people in the United States or approximately 1,200 to 1,900 annually. With a median disease duration approaching 10 years, 4 approximately 12,000 to 19,000 patients are living with Waldenstrom’s macroglobulinemia in the United States.
Turner announced, in a Dec. 11 interview with People, that he'd been diagnosed with an incurable form of bone marrow cancer called Waldenstrom macroglobulinemia. In an interview with People ...
The Golden Bachelor star Gerry Turner says he's been diagnosed with a rare form of cancer called Waldenström's macroglobulinemia. (Ben Hider/ABC via Getty Images) (Ben Hider via Getty Images)
Shortly after he was diagnosed with Waldenström's macroglobulinemia, a bone marrow cancer. Considered a type of Non-Hodgkin lymphoma, the condition converts some white blood cells into cancerous ...
Waldenström first described, in 1944, patients with a disease that has subsequently been named for him, Waldenström's macroglobulinemia, a "hyperviscosity syndrome" in which symptoms are caused by abnormal lymphocytes that prevent normal bone marrow function, which causes anemia and hepatosplenomegaly, and secrete large immunoglobulins ...
Waldenström macroglobulinemia is a slow-silent disease that typically develops when a person is around 65 or older, is male, has a family history of lymphoma, and is caucasian. [6] The condition is called Waldenström macroglobulinemia because the abnormal cells generate excessive levels of IgM which is the biggest immunoglobulin protein, and ...
“We are encouraged by the emerging positive data from NX-5948 in patients with Waldenstrom’s macroglobulinemia, which add to the previously disclosed robust clinical activity observed in patients with chronic lymphocytic leukemia,” said Paula G. O’Connor, M.D., chief medical officer of Nurix.