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Daflon is under preliminary research for its potential use in treating vein diseases, [5] or hemorrhoids. [6] It is sold as a drug in France, [7] [8] Spain, [9] Malaysia [10] [11] and Belgium. There is moderate certainty evidence for the effectiveness of daflon for slightly reducing oedema compared to placebo in the treatment of chronic venous ...
Calcium dobesilate is a vasoprotective.It is the calcium salt of dobesilic acid.It is a synthetic molecule with the ability to reduce capillary permeability in the body. In Switzerland the drug is sold by the pharmaceutical company OM Pharma under the trade name of Doxium in capsules containing 500 mg of active ingredient.
Diosmin is a dietary supplement used to aid treatment of hemorrhoids and venous diseases, i.e., chronic venous insufficiency including spider and varicose veins, leg swelling , stasis dermatitis and venous ulcers. [1] The mechanism of action of Diosmin and other phlebotonics is undefined, [1] and clinical evidence of benefit is limited. [1]
Deaths that have occurred from diflunisal usually involved mixed drugs and or extremely high dosage. The oral LD 50 is 500 mg/kg. Symptoms of overdose include coma, tachycardia, stupor, and vomiting. The lowest dose without the presence of other medicines which caused death was 15 grams.
Hydroxyethylrutosides are used in the treatment of chronic venous insufficiency [2] and hypertensive microangiopathy. [3] Oxerutins work by reducing leakage from the small blood vessels (capillaries). [4] Hydroxyethylrutosides have been used as an alternative to horse chestnut preparations containing aescin. Typical doses are in the order of ...
Dapsone is commonly used in combination with rifampicin and clofazimine for the treatment of leprosy. [4] It is also used to both treat and prevent pneumocystis pneumonia (PCP). [4] [10] It is also used for toxoplasmosis in people unable to tolerate trimethoprim with sulfamethoxazole. [10]
In Romania metamizole is available as the original marketed pharmaceutical product by Zentiva as Algocalmin, as 500 mg immediate release tablets. It's also available as an injection with 1 g of metamizole sodium dissolved in 2 ml of solvent. In Israel it is sold under the brand name "Optalgin" (Hebrew: אופטלגין), manufactured by Teva.
Diloxanide generally has mild side effects. [3] Side effects may include flatulence, vomiting, and itchiness. [1] During pregnancy it is recommended that it be taken after the first trimester. [1] It is a luminal amebicide meaning that it only works on infections within the intestines. [2] Diloxanide came into medical use in 1956. [3]