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Beta-blockers. Calcium-channel blockers. Disopyramide. Dilated cardiomyopathy is one of the main causes of heart failure. It occurs in about 1 in 2,500 people. Treatment for dilated cardiomyopathy ...
Beta blockers vary in their lipophilicity (fat solubility) and in turn in their ability to cross the blood–brain barrier and exert effects in the central nervous system. [76] Beta blockers with greater blood–brain barrier permeability can have both neuropsychiatric therapeutic benefits and side effects, as well as adverse cognitive effects ...
The Cleveland Clinic classified beta blockers into two categories, cardioselective and nonselective, according to its website. The latter is for medicines that block the B1 receptors found in the ...
Beta-blockers act as competitive antagonists that block the effects of catecholamines at beta-adrenergic receptor sites, resulting in reduced rate and force of contraction of the heart, as well as reduced peripheral vascular resistance. [14] Non-selective beta-blockers: propranolol, nadolol, timolol
Medications used include: diuretic agents, vasodilator agents, positive inotropes, ACE inhibitors, beta blockers, and aldosterone antagonists (e.g., spironolactone). Some medications which increase heart function, such as the positive inotrope milrinone, lead to increased death, and are contraindicated. [9] [10]
Their early use is contraindicated if there are signs of congestive heart failure (e.g., Killip class II or above) or hypotension, along with other contraindications to beta blockers (slow heart rate, atrioventricular block); in the absence of contraindications beta blocker therapy should begin in the first 24 hours. It may be prudent to prefer ...
Along with beta blockers and digoxin, calcium channel blockers have one of the highest rates of death in overdose. [2] These medications first became available in the 1970s and 1980s. [2] They are one of the few types of medication in which one pill can result in the death of a child. [2]
Landiolol, sold under the brand name Onoact among others, is a medication used for the treatment of tachycardia, atrial fibrillation, and atrial flutter. [1] [4] It is a beta-adrenergic blocker; [4] an ultra short-acting, β1-superselective intravenous adrenergic antagonist, which decreases the heart rate effectively with less negative effect on blood pressure or myocardial contractility.