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In medicine, pleocytosis (or pleiocytosis) is an increased cell count (from Greek pleion, "more"), particularly an increase in white blood cell count, in a bodily fluid, such as cerebrospinal fluid. [1] It is often defined specifically as an increased white blood cell count in cerebrospinal fluid. [2]
Lymphocytic pleocytosis is an abnormal increase in the amount of lymphocytes in the cerebrospinal fluid (CSF). It is usually considered to be a sign of infection or inflammation within the nervous system , and is encountered in a number of neurological diseases , such as pseudomigraine, Susac's syndrome, and encephalitis.
Chronic meningitis is defined by signs and symptoms being present longer than four weeks and includes pleocytosis, or the presence of inflammatory cells in the cerebrospinal fluid. [2] The initial test is usually a lumbar puncture to collect cerebrospinal fluid for analysis.
In most of these patients, CSF analysis showed lymphocytic pleocytosis. A recent study identified an underlying neoplasia in 27% of these patients, mostly thymomas. [ 13 ] Similar to that seen in patients with anti-gamma-aminobutyric acid B receptor (GABA-BR) and anti-AMPAR antibodies, they may also present with coexisting autoimmune disorders ...
If tested in the prodromal phase, cerebrospinal fluid pleocytosis is found in more than 80% of cases, [6] [7] with mainly lymphocytes. [7] This pleocytosis resolves in about 8 weeks even if chronic uveitis persists. [7] Functional tests may include electroretinogram and visual field testing. [2]
Laboratory studies that support diagnosis of AHL are: peripheral leukocytosis, cerebrospinal fluid (CSF) pleocytosis associated with normal glucose and increased protein. On magnetic resonance imaging (MRI), lesions of AHL typically show extensive T2-weighted and fluid-attenuated inversion recovery (FLAIR) white matter hyperintensities with ...
Mollaret's meningitis is characterized by chronic, recurrent episodes of headache, stiff neck, meningismus, and fever; cerebrospinal fluid (CSF) pleocytosis with large "endothelial" cells, neutrophil granulocytes, and lymphocytes; and attacks separated by symptom-free periods of weeks to years; and spontaneous remission of symptoms and signs.
This is a shortened version of the fourth chapter of the ICD-9: Diseases of the Blood and Blood-forming Organs.It covers ICD codes 280 to 289.The full chapter can be found on pages 167 to 175 of Volume 1, which contains all (sub)categories of the ICD-9.