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Ibuprofen is a weaker anti-inflammatory agent than other NSAIDs. [10] Ibuprofen was discovered in 1961 by Stewart Adams and John Nicholson [12] while working at Boots UK Limited and initially marketed as Brufen. [13] It is available under a number of brand names including Advil, Motrin, and Nurofen.
Hepatotoxicity (from hepatic toxicity) implies chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval.
Common adverse drug reactions (ADR), other than listed above, include: raised liver enzymes, headache, dizziness. [17] Uncommon ADRs include an abnormally high level of potassium in the blood, confusion, spasm of the airways, and rash. [17] Ibuprofen may also rarely cause irritable bowel syndrome symptoms.
Due to the risk of liver damage, ... “A doctor might recommend Tylenol over ibuprofen for patients who need pain relief but cannot tolerate NSAIDs due to stomach issues, risk of bleeding, or ...
Still, it’s important that you avoid things that hurt your liver such as excess alcohol, recreational drugs, and some dietary supplements, said Bansal. “Moderation is the key to everything."
Fatty liver disease happens when fat builds up in your liver. This can cause damage, inflammation, and other complications. There are two main types of fatty liver disease: