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Alcoholic polyneuropathy usually has a gradual onset over months or even years, although axonal degeneration often begins before an individual experiences any symptoms. [2] The disease typically involves sensory issues and motor loss, as well as painful physical perceptions, though all sensory modalities may be involved. [3]
That dangly thing in the back of your throat (a.k.a. your uvula) is pretty important—it helps you swallow your food, allowing you to eat and speak properly. ... What causes a swollen uvula? 1 ...
A protracted alcohol withdrawal syndrome occurs in many alcoholics when withdrawal symptoms continue beyond the acute withdrawal stage but usually at a subacute level of intensity and gradually decreasing with severity over time. This syndrome is sometimes referred to as the post-acute-withdrawal syndrome. Some withdrawal symptoms can linger ...
Alcoholic ketoacidosis is caused by complex physiology that is the result of prolonged and heavy alcohol intake, usually in the setting of poor nutrition. Chronic alcohol use can cause depleted hepatic glycogen stores and ethanol metabolism further impairs gluconeogenesis.
Delirium tremens is a component of alcohol withdrawal hypothesized to be the result of compensatory changes in response to chronic heavy alcohol use. Alcohol positively allosterically modulates the binding of GABA, enhancing its effect and resulting in inhibition of neurons projecting into the nucleus accumbens, as well as inhibiting NMDA ...
Back pain. When your back aches and there’s no obvious cause (like lifting heavy boxes or falling), inflammation could be the root cause. Inflammatory back pain tends to come on gradually and ...
If you have an inherited intolerance to alcohol, a mutated gene could be the culprit. An at-home DNA test could detect whether you have the mutation, but doctors say there could be some drawbacks.
The reaction is the result of an accumulation of acetaldehyde, a metabolic byproduct of the catabolic metabolism of alcohol, and is caused by an aldehyde dehydrogenase 2 deficiency. [4] This syndrome has been associated with lower than average rates of alcoholism, possibly due to its association with adverse effects after drinking alcohol. [5]