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The formula for the difference of two squares can be used for factoring polynomials that contain the square of a first quantity minus the square of a second quantity. For example, the polynomial x 4 − 1 {\displaystyle x^{4}-1} can be factored as follows:
Fermat's factorization method, named after Pierre de Fermat, is based on the representation of an odd integer as the difference of two squares: N = a 2 − b 2 . {\displaystyle N=a^{2}-b^{2}.} That difference is algebraically factorable as ( a + b ) ( a − b ) {\displaystyle (a+b)(a-b)} ; if neither factor equals one, it is a proper ...
More generally, the difference of the squares of two numbers is the product of their sum and their difference. That is, = (+) This is the difference-of-squares formula, which can be useful for mental arithmetic: for example, 47 × 53 can be easily computed as 50 2 − 3 2 = 2500 − 9 = 2491.
The squared Euclidean distance between two points, equal to the sum of squares of the differences between their coordinates; Heron's formula for the area of a triangle can be re-written as using the sums of squares of a triangle's sides (and the sums of the squares of squares) The British flag theorem for rectangles equates two sums of two squares
The result of fitting a set of data points with a quadratic function Conic fitting a set of points using least-squares approximation. In regression analysis, least squares is a parameter estimation method based on minimizing the sum of the squares of the residuals (a residual being the difference between an observed value and the fitted value provided by a model) made in the results of each ...
The general regression model with n observations and k explanators, the first of which is a constant unit vector whose coefficient is the regression intercept, is = + where y is an n × 1 vector of dependent variable observations, each column of the n × k matrix X is a vector of observations on one of the k explanators, is a k × 1 vector of true coefficients, and e is an n× 1 vector of the ...
The explained sum of squares (ESS) is the sum of the squares of the deviations of the predicted values from the mean value of a response variable, in a standard regression model — for example, y i = a + b 1 x 1i + b 2 x 2i + ... + ε i, where y i is the i th observation of the response variable, x ji is the i th observation of the j th ...
In bioinformatics, the root mean square deviation of atomic positions is the measure of the average distance between the atoms of superimposed proteins. In structure based drug design, the RMSD is a measure of the difference between a crystal conformation of the ligand conformation and a docking prediction.