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Alcoholic liver disease (ALD), also called alcohol-related liver disease (ARLD), is a term that encompasses the liver manifestations of alcohol overconsumption, including fatty liver, alcoholic hepatitis, and chronic hepatitis with liver fibrosis or cirrhosis. [1]
Alcohol is also directly damaging to liver cells. Alcohol is metabolized to acetaldehyde in the liver via the enzymes CYP2E1 and aldehyde dehydrogenase. [7] Acetaldehyde forms reactive oxygen species in the liver as well as acting as a DNA adduct (binding to DNA) leading to direct hepatocyte damage. [7]
“The key to preventing liver disease is avoiding things that may be harmful to the liver, including alcohol and unhealthy foods,” says Dr. Allyce Caines, MD, a transplant hepatologist and ...
Numerous scientific studies have shown how even moderate alcohol consumption negatively impacts the body, upping the risk for liver damage, heart attacks, stroke and osteoporosis.
A new federal report shows that one drink per day could raise the risk of liver damage and several cancers. The report follows a recommendation by the U.S. Surgeon General on safe alcohol ...
A liver can be damaged by chronic alcohol use, leading to a buildup of fat and scar tissue. [2] The reduced ability of such a liver to metabolize or break down alcohol means that small amounts can lead to a high blood alcohol concentration (BAC) and more rapid intoxication.