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Lemierre's syndrome is infectious thrombophlebitis of the internal jugular vein. [2] It most often develops as a complication of a bacterial sore throat infection in young, otherwise healthy adults. The thrombophlebitis is a serious condition and may lead to further systemic complications such as bacteria in the blood or septic emboli .
This bacterium has been found to be associated with the foot disease thrush in horses. Thrush is a common infection that occurs on the hoof of a horse, specifically in the region of the frog. F. necrophorum occurs naturally in the animal's environment, especially in wet, muddy, or unsanitary conditions, such as an unclean stall.
Strains of Fusobacterium can cause several human diseases and infections, including periodontal diseases, Lemierre's syndrome, [8] oral, head, and neck infections, as well as colorectal cancer and topical skin ulcers. [9] It has been tied [clarification needed] to HIV infection and suboptimal immune recovery. [10]
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Rarely, the infection may spread beyond the tonsil resulting in inflammation and infection of the internal jugular vein giving rise to a spreading infectious thrombophlebitis (Lemierre's syndrome). [citation needed] In strep throat, diseases like post-streptococcal glomerulonephritis [non-primary source needed] [44] can occur. These ...
Fusobacterium nucleatum is a Gram-negative, anaerobic bacterium, commensal to the human oral cavity, that plays a role in periodontal disease. This organism is commonly recovered from different monocultured microbial and mixed infections in humans and animals.
Pharyngitis is a type of upper respiratory tract infection. [7] Most cases are caused by a viral infection. [2] Strep throat, a bacterial infection, is the cause in about 25% of children and 10% of adults. [2] Uncommon causes include other bacteria such as gonococcus, fungi, irritants such as smoke, allergies, and gastroesophageal reflux disease.
Necrotizing periodontal diseases are caused by a mixed bacterial infection that includes anaerobes such as P. intermedia [1] and Fusobacterium as well as spirochetes, such as Treponema. [3] Necrotizing gingivitis may also be associated with diseases in which the immune system is compromised, including HIV/AIDS. [1]