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Hypomelanic macules ("ash leaf spots") are present in about 90% of people with TSC. [11] These small white or lighter patches of skin may appear anywhere on the body, and are caused by a lack of melanin. They are usually the only visible sign of TSC at birth. In fair-skinned individuals, a Wood's lamp (ultraviolet light) may be required to see ...
Tuberous sclerosis: Von Hippel–Lindau disease: See also. List of skin conditions; List of allergens; List of cutaneous conditions associated with increased risk of ...
Café au lait spots, or café au lait macules, are flat, hyperpigmented birthmarks. [1] The name café au lait is French for "coffee with milk" and refers to their light-brown color. They are caused by a collection of pigment-producing melanocytes in the epidermis of the skin. [ 2 ]
The term phakomatosis originated in 1923, when the Dutch ophthalmologist van der Hoeve [3] used the term phakoma to refer to a "mother spot" or birthmark, [3] a physical characteristic common to patients with tuberous sclerosis and neurofibromatosis that he examined. [3] The term phakomatoses was derived from phakos, [4] the Greek term for ...
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The history of tuberous sclerosis (TSC) research spans less than 200 years. TSC is a rare, multi-system genetic disease that can cause benign tumours to grow on the brain or other vital organs such as the kidneys , heart , eyes , lungs , and skin .
Subependymal giant cell astrocytoma (SEGA, SGCA, or SGCT) is a low-grade astrocytic brain tumor (astrocytoma) that arises within the ventricles of the brain. [1] It is most commonly associated with tuberous sclerosis complex (TSC).
In fact, another phrase commonly associated with Ash Wednesday, "ashes to ashes and dust to dust," comes from the Church of England's Book of Common Prayer. It's found in the order of service for ...