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Hypotension, also known as low blood pressure, is a cardiovascular condition characterized by abnormally reduced blood pressure. [1] Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood [2] and is indicated by two numbers, the systolic blood pressure (the top number) and the diastolic blood pressure (the bottom number), which are the ...
In addition to the myoglobinuria, two other mechanisms contribute to kidney impairment: low blood pressure leads to constriction of the blood vessels and therefore a relative lack of blood flow to the kidney, and finally uric acid may form crystals in the tubules of the kidneys, causing obstruction.
Kidney ischemia [1] is a disease with a high morbidity and mortality rate. [2] Blood vessels shrink and undergo apoptosis which results in poor blood flow in the kidneys. More complications happen when failure of the kidney functions result in toxicity in various parts of the body which may cause septic shock, hypovolemia, and a need for surgery. [3]
Individuals with poor kidney perfusion are especially at risk for kidney impairment inherent with these medications. [15] Beta-blockers. Beta-blockers are stopped or decreased in people with acutely decompensated heart failure and a low blood pressure. However, continuation of beta-blockers may be appropriate if the blood pressure is adequate. [16]
Blood pressure that is too low is called hypotension, pressure that is consistently too high is called hypertension, and normal pressure is called normotension. [9] Both hypertension and hypotension have many causes and may be of sudden onset or of long duration.
Dialysis is an imperfect treatment to replace kidney function because it does not correct the compromised endocrine functions of the kidney. Dialysis treatments replace some of these functions through diffusion (waste removal) and ultrafiltration (fluid removal). [6] Dialysis uses highly purified (also known as "ultrapure") water. [7]
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