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The endometrium is the innermost lining layer of the uterus, and functions to prevent adhesions between the opposed walls of the myometrium, thereby maintaining the patency of the uterine cavity. [12] During the menstrual cycle or estrous cycle, the endometrium grows to a thick, blood vessel-rich, glandular tissue layer.
Transvaginal ultrasonography is generally done before obtaining an endometrial biopsy as it may help in the gynecologic diagnosis, or even make the taking of a biopsy superfluous if the lining is thin. If the endometrial lining is less than 5 mm thick on sonography, it is highly unusual to encounter endometrial cancer. [1]
Endometrial cancer is a cancer that arises from the endometrium (the lining of the uterus or womb). [1] It is the result of the abnormal growth of cells that have the ability to invade or spread to other parts of the body. [8] The first sign is most often vaginal bleeding not associated with a menstrual period. [1]
But in the new study, which included data for about 1,500 Black patients, more than 11% of those with endometrial cancer (24 of 210 people) had endometrial thickness measurements that fell within ...
The decidua is the modified mucosal lining of the uterus (that is, modified endometrium) that forms every month, in preparation for pregnancy. It is shed off each month when there is no fertilized egg to support. [1] The decidua is under the influence of progesterone. Endometrial cells become highly characteristic.
The finding on transvaginal ultrasound of a thin endometrial lining gives the physician a 99% negative predictive value that the patient does not have endometrial cancer. [3] If a patient had a prior endometrial sampling that was inconclusive, then a transvaginal ultrasound can be used to triage a woman with post-menopausal bleeding. [3]
An endometrial polyp or uterine polyp is a mass in the inner lining of the uterus. [1] They may have a large flat base or be attached to the uterus by an elongated pedicle (pedunculated). [2] [3] Pedunculated polyps are more common than sessile ones. [4] They range in size from a few millimeters to several centimeters. [3]
Endometrial intraepithelial neoplasia (EIN) is a premalignant lesion of the uterine lining that predisposes to endometrioid endometrial adenocarcinoma. It is composed of a collection of abnormal endometrial cells, arising from the glands that line the uterus , which have a tendency over time to progress to the most common form of uterine cancer ...