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Contrary to what its name suggests, antidepressant medication is prescribed to treat more than clinical depression. The Food and Drug Administration has approved certain antidepressants to treat ...
The number of people with depression has reached new highs—and so has antidepressant use. As Americans are increasingly reaching for pharmaceutical solutions for depression—about one in eight ...
With TRD, depression doesn’t always improve through standard treatments, like antidepressants or psychotherapy. If you have treatment-resistant depression, or your depression doesn’t respond ...
Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1] They act by antagonizing the α 2 -adrenergic receptor and certain serotonin receptors such as 5-HT 2A and 5-HT 2C , [ 1 ] but also 5-HT 3 , [ 1 ] 5-HT 6 , and/or 5-HT 7 in some cases.
Sequenced Treatment Alternatives to Relieve Depression (STAR*D) was a collaborative study on the treatment of depression, funded by the National Institute of Mental Health. Its main focus was on the treatment of depression in patients where the first prescribed antidepressant proved inadequate.
The authors attributed the relationship between severity and efficacy to a reduction of the placebo effect in severely depressed patients, rather than an increase in the effect of the medication. [11] Some researchers have questioned the statistical basis of this study suggesting that it underestimates the effect size of antidepressants. [12] [13]
Researchers say members of the group who chose antidepressants were slightly more depressed than the members of the group that chose to take running. “This study gave anxious and depressed ...
The Emperor's New Drugs: Exploding the Antidepressant Myth is a 2009 book by Irving Kirsch, arguing that the chemical imbalance theory of depression is wrong and that antidepressants have little or no direct effect on depression but, because of their common or serious side-effects, they are powerful active placebos.
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