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TaqMan probes are hydrolysis probes that are designed to increase the specificity of quantitative PCR.The method was first reported in 1991 by researcher Kary Mullis at Cetus Corporation, [1] and the technology was subsequently developed by Hoffmann-La Roche for diagnostic assays and by Applied Biosystems (now part of Thermo Fisher Scientific) for research applications.
Primer-Probe design, Chimera finding FASTA, FASTQ, GenBank Free, GPL: No Mac OS, Windows Official website: Discovery Studio Yes Align123, ClustalW, S-ALIGN UPGMA, NJ, with bootstrap and best tree Visualizer supports 2D and 3D structure and sequence; full version has comprehensive functionality for protein, nucleotides, more
The package contains additional tools for data import and export, sequence alignment, primary and secondary structure editing, profile and filter calculation, phylogenetic analyses, specific hybridization probe design and evaluation, and other components for data analysis. The latest version of the software was released in 2021. [3]
List of free analog and digital electronic circuit simulators, available for Windows, macOS, Linux, and comparing against UC Berkeley SPICE.The following table is split into two groups based on whether it has a graphical visual interface or not.
(3) During PCR, the probe is degraded by the Taq polymerase and the fluorescent reporter released. Fluorescent reporter probes detect only the DNA containing the sequence complementary to the probe; therefore, use of the reporter probe significantly increases specificity, and enables performing the technique even in the presence of other dsDNA ...
List of software for Monte Carlo molecular modeling; Comparison of software for molecular mechanics modeling; Molecular design software; Molecule editor; Molecular modeling on GPUs; List of software for nanostructures modeling; Semi-empirical quantum chemistry method; Computational chemical methods in solid-state physics, with periodic boundary ...
For passive planar elements development, integrated into Keysight EEsof Advanced Design System. Ansys HFSS: commercial Yes Yes Yes Yes Yes Automatic adaptive FEM, FDTD, PO, Hybrid FEBI, MoM, and Eigenmode expansion (EME).
Taq polymerase is a thermostable DNA polymerase I named after the thermophilic eubacterial microorganism Thermus aquaticus, from which it was originally isolated by master's student Alice Chien et al. in 1976. [1]
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