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Signs and symptoms of aspiration pneumonia may develop gradually, with increased respiratory rate, foul-smelling sputum, hemoptysis, and fever. Complications may occur, such as exudative pleural effusion, empyema, and lung abscesses. [4] If left untreated, aspiration pneumonia can progress to form a lung abscess. [5]
Aspiration can result in patient death through a variety of mechanisms. It is important to recognize and diagnose early in order to improve patient outcomes. Death from aspiration and aspiration-related syndromes is most common in elderly patients with known baseline risk factors, though it frequently goes unrecognized. [18]
Daiichi, working with Johnson & Johnson as it had with ofloxacin, obtained FDA approval in 1996 under the brand name Levaquin [65] to treat bacterial sinusitus, bacterial exacerbations of bronchitis, community-acquired pneumonia, uncomplicated skin infections, complicated urinary tract infections, and acute pyelonephritis.
Additional consideration is given to the treatment setting; most patients are cured by oral medication, while others must be hospitalized for intravenous therapy or intensive care. Current treatment guidelines recommend a beta-lactam, like amoxicillin, and a macrolide, like azithromycin or clarithromycin, or a quinolone , such as levofloxacin .
In infants, RSV can cause bronchiolitis (inflammation of the small airways in the lung) and pneumonia. In adults, RSV can sometimes lead to such serious conditions as asthma, chronic pulmonary ...
Mycobacterium avium-intracellulare infection (MAI) is an atypical mycobacterial infection, i.e. one with nontuberculous mycobacteria or NTM, caused by Mycobacterium avium complex (MAC), which is made of two Mycobacterium species, M. avium and M. intracellulare. [1]
It is life-threatening in the elderly or those who are immunocompromised. [13] [14] The most common treatment is antibiotics and these vary in their adverse effects and their effectiveness. [13] [15] Pneumonia is also the leading cause of death in children less than five years of age in low income countries. [15]
If the foreign body does not cause a large degree of obstruction, patients may present with chronic cough, asymmetrical breath sounds on exam, or recurrent pneumonia of a specific lung lobe. [2] If the aspiration occurred weeks or even months ago, the object may lead to an obstructive pneumonia or even a lung abscess.