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The minimum inhibitory concentration (MIC) and minimum bactericidal concentration are used to measure in vitro activity of antimicrobial agents. They are good indicators of antimicrobial potency, but don't give any information relating to time-dependent antimicrobial killing (the so-called post antibiotic effect).
In pharmacology, potency or biological potency [1] is a measure of a drug's biological activity expressed in terms of the dose required to produce a pharmacological effect of given intensity. [2]
Topics of pharmacodynamics. Pharmacodynamics (PD) is the study of the biochemical and physiologic effects of drugs (especially pharmaceutical drugs).The effects can include those manifested within animals (including humans), microorganisms, or combinations of organisms (for example, infection).
[9] [10] MIC values provide a quantitative measure of an extract or compound's antimicrobial potency. The lower the MIC, the more potent the antimicrobial. [4] When in vitro toxicity data is available, MICs can also be used to calculate selectivity index values, a measure of off-target to target toxicity. [4]
In pharmacology, an effective dose (ED) or effective concentration (EC) is the dose or concentration of a drug that produces a biological response. [1] [2] The term "effective dose" is used when measurements are taken in vivo, while "effective concentration" is used when the measurements are taken in vitro.
The cars were on several streets that were flooded following a major water main break on Monday, which triggered dramatic rescues and impacted over 400 homes in the area. At least 130 households ...
It is commonly used as a measure of a drug's potency, although the use of EC 50 is preferred over that of 'potency', which has been criticised for its vagueness. [3] EC 50 is a measure of concentration, expressed in molar units (M), where 1 M is equivalent to 1 mol / L .
“A certain nature of the thing, you forget what got us here and think because we got there (last year), we’ll get there naturally,” Gobert said.