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  2. Relationship between telomeres and longevity - Wikipedia

    en.wikipedia.org/wiki/Relationship_between...

    [10] [11] Examining telomeres is one of the most important fields of research related to aging. It is also very important to investigate the mechanisms of maintaining telomerase, cell cleansing ( old cells that accumulate in tissues and sometimes cause cancer and inflammation) and the production of new cells in long-lived organisms.

  3. Evolution of ageing - Wikipedia

    en.wikipedia.org/wiki/Evolution_of_ageing

    The first modern theory of mammal ageing was formulated by Peter Medawar in 1952. This theory formed in the previous decade with J. B. S. Haldane and his selection shadow concept. The development of human civilization has shifted the selective shadow as the conditions that humans now live in include improved quality of victuals, living ...

  4. Ageing - Wikipedia

    en.wikipedia.org/wiki/Ageing

    This is an accepted version of this page This is the latest accepted revision, reviewed on 13 February 2025. Biological process of getting older This article is about ageing specifically in humans. For the ageing of whole organisms including animals, see Senescence. For other uses, see Ageing (disambiguation). Part of a series on Human growth and development Stages Gamete Zygote Embryo Fetus ...

  5. Mutation accumulation theory - Wikipedia

    en.wikipedia.org/wiki/Mutation_accumulation_theory

    (a) The survival rate within a population decreases with age, while the reproduction rate remains constant.(b) The reproduction probability peaks early in life, at sexual maturity, and then steadily decreases as an individual ages, with the remaining share of the population decreasing with age as they enter the selection shadow.

  6. Antagonistic pleiotropy hypothesis - Wikipedia

    en.wikipedia.org/wiki/Antagonistic_pleiotropy...

    Strength of natural selection plot as a function of age. The antagonistic pleiotropy hypothesis (APT) is a theory in evolutionary biology that suggests certain genes may confer beneficial effects early in an organism's life, enhancing reproductive success, while also causing detrimental effects later in life, contributing to the aging process.

  7. Category:Theories of ageing - Wikipedia

    en.wikipedia.org/wiki/Category:Theories_of_ageing

    Help. Subcategories. This category has the following 2 subcategories, out of 2 total. T. Theories of biological ageing (2 ... Aging by design theory;

  8. Disposable soma theory of aging - Wikipedia

    en.wikipedia.org/.../Disposable_soma_theory_of_aging

    In biogerontology, the disposable soma theory of aging states that organisms age due to an evolutionary trade-off between growth, reproduction, and DNA repair maintenance. [1] Formulated by British biologist Thomas Kirkwood , the disposable soma theory explains that an organism only has a limited amount of resources that it can allocate to its ...

  9. Network theory of aging - Wikipedia

    en.wikipedia.org/wiki/Network_theory_of_aging

    Organisms- As individuals age, their social networks begin to decline. Only thing remaining is the contacts for the most important social functions. Cognitive deterioration due to aging and loss of support systems leads to more declines in old age. [5] Social groups- A decline in social groups mimics the declines associated with the aging ...