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  2. Valsartan - Wikipedia

    en.wikipedia.org/wiki/Valsartan

    Valsartan, sold under the brand name Diovan among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease. [8] It belongs to a class of medications referred to as angiotensin II receptor blockers (ARBs). It is a reasonable initial treatment for high blood pressure. [8] It is taken by mouth. [8]

  3. Discovery and development of angiotensin receptor blockers

    en.wikipedia.org/wiki/Discovery_and_development...

    Valsartan, first marketed by Novartis, is a nonheterocyclic ARB, where the imidazole of losartan has been replaced by an acylated amino acid. [ 1 ] Irbesartan was developed by Sanofi Research and is longer acting than valsartan and losartan and it has an imidazolinone ring where a carbonyl group functions as a hydrogen bond acceptor instead of ...

  4. Analgesic nephropathy - Wikipedia

    en.wikipedia.org/wiki/Analgesic_nephropathy

    Data from Switzerland, for example, demonstrated a decline in the prevalence of analgesic nephropathy among people with end-stage kidney disease, from 28% in 1981 to 12% in 1990. [4] An autopsy study performed in Switzerland suggested that the prevalence of analgesic nephropathy in the general population has likewise decreased; the prevalence ...

  5. Valsartan/hydrochlorothiazide - Wikipedia

    en.wikipedia.org/wiki/Valsartan/hydrochlorothiazide

    Valsartan/hydrochlorothiazide, sold under the brand name Diovan HCT among others, is a medication used to treat high blood pressure when valsartan is not sufficient. [6] It is a combination of valsartan, an angiotensin receptor blocker with hydrochlorothiazide, a diuretic. [7] It is taken by mouth. [7] Common side effects include dizziness and ...

  6. Sacubitril/valsartan - Wikipedia

    en.wikipedia.org/wiki/Sacubitril/valsartan

    Sacubitril/valsartan is co-crystallized sacubitril and valsartan, in a one-to-one molar ratio. One sacubitril/valsartan complex consists of six sacubitril anions, six valsartan dianions, 18 sodium cations, and 15 molecules of water, resulting in the molecular formula C 288 H 330 N 36 Na 18 O 48 ·15H 2 O and a molecular mass of 5748.03 g/mol ...

  7. Loop diuretic - Wikipedia

    en.wikipedia.org/wiki/Loop_diuretic

    They are often used for the treatment of hypertension and edema secondary to congestive heart failure, liver cirrhosis, or chronic kidney disease. While thiazide diuretics are more effective in patients with normal kidney function, loop diuretics are more effective in patients with impaired kidney function.

  8. RIP, Caitlyn the Dog, a Canine Trailblazer - AOL

    www.aol.com/rip-caitlyn-dog-canine-trailblazer...

    Watch the Video. Click here to watch on YouTube. Caitlyn the dog passed away Sunday after being diagnosed with cancer 10 years after making national headlines for a horrific animal abuse case ...

  9. Familial renal disease in animals - Wikipedia

    en.wikipedia.org/wiki/Familial_renal_disease_in...

    Samoyeds can be affected by basement membrane disease of the kidneys. It is inherited through the X chromosome and is therefore more severe in affected male dogs. Findings in male dogs include the presence of protein and glucose in the urine and the inability to concentrate urine, and progression to kidney failure by the age of 9 months and death by 16 months. [3]