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The split gene theory is a theory of the origin of introns, long non-coding sequences in eukaryotic genes between the exons. [1] [2] [3] The theory holds that the randomness of primordial DNA sequences would only permit small (< 600bp) open reading frames (ORFs), and that important intron structures and regulatory sequences are derived from stop codons.
The replicator is the entire DNA sequence (including, but not limited to the origin of replication) required to direct the initiation of DNA replication. The initiator is the protein that recognizes the replicator and activates replication initiation.
Origin recognition in eukaryotes other than S. cerevisiae or its close relatives does not conform to the sequence-specific read-out of conserved origin DNA elements. Pursuits to isolate specific chromosomal replicator sequences more generally in eukaryotic species, either genetically or by genome-wide mapping of initiator binding or replication ...
Deoxyribonucleic acid (/ d iː ˈ ɒ k s ɪ ˌ r aɪ b oʊ nj uː ˌ k l iː ɪ k,-ˌ k l eɪ-/ ⓘ; [1] DNA) is a polymer composed of two polynucleotide chains that coil around each other to form a double helix. The polymer carries genetic instructions for the development, functioning, growth and reproduction of all known organisms and many ...
DNA structure and bases A-B-Z-DNA Side View. Tertiary structure refers to the locations of the atoms in three-dimensional space, taking into consideration geometrical and steric constraints. It is a higher order than the secondary structure, in which large-scale folding in a linear polymer occurs and the entire chain is folded into a specific 3 ...
The double helix is the dominant tertiary structure for biological DNA, and is also a possible structure for RNA. Three DNA conformations are believed to be found in nature, A-DNA, B-DNA, and Z-DNA. The "B" form described by James D. Watson and Francis Crick is believed to predominate in cells. [2]
Spanish scientists said they will reveal details of the nationality of 15th-century explorer Christopher Columbus on Saturday, after using DNA analysis to tackle a centuries-old mystery. Countries ...
The equalities G = C and A = T suggested that these bases were paired, this pairing being the basis of the DNA structure that is now known to be correct. Conversely the inequalities G ≠ A etc. meant that DNA could not have a systematic repetition of a fundamental unit, as required by the tetranucleotide hypothesis.