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Vitiligo (/ ˌ v ɪ t ɪ ˈ l aɪ ɡ oʊ /, vi-ti-leye-goh) is a chronic autoimmune disorder that causes patches of skin to lose pigment or color. [1] The cause of vitiligo is unknown, but it may be related to immune system changes, genetic factors, stress, or sun exposure.
To the hands and legs PUVA may be more effective. The reason can be because UVA penetrates deeper in the skin, and the melanocytes in the skin of the hands and legs are positioned deeper in the skin. Narrowband UVB 311 nanometer is blocked by the topmost skin layer, and UVA 365 nanometer reaches the melanocytes that are in the bottom skin layer.
Vitiligo of the hand in a person with dark skin. The World Vitiligo Day, observed on June 25, is an initiative aimed to build global awareness about vitiligo.Vitiligo occurs in 1–2% of the population worldwide; a change of color in the skin creating a variety of patterns on the skin from the loss of pigment.
Depigmentation is the lightening of the skin or loss of pigment. Depigmentation of the skin can be caused by a number of local and systemic conditions. The pigment loss can be partial (injury to the skin) or complete (caused by vitiligo). It can be temporary (from tinea versicolor) or permanent (from albinism). [1]
Vitiligo's drastic effects on the body can cause psychological distress. Jackson used fair-colored makeup, [3] and possibly skin-bleaching prescription creams, [4] to cover up the uneven blotches of color caused by the illness. The creams would have further lightened his skin, and, with the application of makeup, he could appear very pale. [14]
The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin, the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [3]
Poliosis is present in half of patients with segmental vitiligo. [ 5 ] Vogt-Koyanagi-Harada Syndrome (VKH): VKH is a systemic autoimmune disorder affecting melanin-containing tissues, leading to uveitis , meningitis , and poliosis, which often involves the eyebrows and eyelashes.
From the age of 40, the skin is less able to regenerate from sun exposure, and liver spots are very common in this age group, particularly in those who spend time in the sun. [7] In the overwhelming majority of cases, liver spots pose no threat and require no treatment, though they occasionally have been known to obscure the detection of skin ...