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Management of ulcerative colitis involves first treating the acute symptoms of the disease, then maintaining remission. Ulcerative colitis is a form of colitis , a disease of the intestine , specifically the large intestine or colon , that includes characteristic ulcers , or open sores, in the colon.
The first-line maintenance medication for ulcerative colitis in remission is mesalazine (also known as mesalamine or 5-ASA). [95] [96] For patients with active disease limited to the left colon (descending colon) or proctitis, mesalazine is also the first-line agent, and a combination of suppositories and oral mesalazine may be tried.
People with ulcerative colitis typically initially suffer from bloody diarrhea, says Dr. Ece A. Mutlu, a professor of medicine and an IBD specialist at Rush University Medical Center in Chicago.
The diet may be used as part of the bowel preparation before a diagnostic procedure such as colonoscopy or as a short-term therapy for acute stages of gastrointestinal illnesses such as Crohn's disease, diverticulitis, bowel obstruction, and ulcerative colitis.
An anti-TL1A monoclonal antibody called tulisokibart may help people with moderate to severe ulcerative colitis achieve clinical remission, a phase 2 trial has found.
“Studies have shown that regular psyllium use may help reduce the severity of symptoms in irritable bowel syndrome, maintain remission in ulcerative colitis, and decrease the risk of colorectal ...