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  2. Anti-allergic agent - Wikipedia

    en.wikipedia.org/wiki/Anti-allergic_agent

    H1-antihistamines are further split into three groups known as the first-generation, second-generation and third-generation antihistamines. Another type of antihistamines known as H2-antihistamines are used to treat gastrointestinal conditions caused by excessive stomach acid. [8] Mechanism

  3. Antihistamine - Wikipedia

    en.wikipedia.org/wiki/Antihistamine

    The introduction of the first-generation antihistamines marked the beginning of medical treatment of nasal allergies. [28] Research into these drugs led to the discovery that they were H 1 receptor antagonists and also to the development of H 2 receptor antagonists , where H 1 -antihistamines affected the nose and the H 2 -antihistamines ...

  4. Hydroxyzine - Wikipedia

    en.wikipedia.org/wiki/Hydroxyzine

    It is a first-generation antihistamine in the piperazine family of chemicals. [8] [4] Common side effects include sleepiness, headache, and dry mouth. [8] [9] Serious side effects may include QT prolongation. [9] It is unclear if use during pregnancy or breastfeeding is safe. [8]

  5. Diphenhydramine - Wikipedia

    en.wikipedia.org/wiki/Diphenhydramine

    Diphenhydramine is a first-generation antihistamine used to treat several conditions including allergic symptoms and itchiness, the common cold, insomnia, motion sickness, and extrapyramidal symptoms. [19] [20] Diphenhydramine also has local anesthetic properties, and has been used as such in people allergic to common local anesthetics such as ...

  6. Which Allergy Medicine Is Actually Most Effective? - AOL

    www.aol.com/lifestyle/allergy-medicine-actually...

    “This is a second-generation antihistamine, which is less sedating than the first-generation antihistamines like Benadryl,” says Shaan Waqar, MD, an allergist and immunologist with ENT and ...

  7. Azatadine - Wikipedia

    en.wikipedia.org/wiki/Azatadine

    Azatadine (Optimine) is a first-generation antihistamine and anticholinergic drug that was synthesized in 1963 by Schering-Plough, a former American pharmaceutical company. [ 1 ] [ 2 ] It was patented in 1967. [ 3 ]

  8. Chlorcyclizine - Wikipedia

    en.wikipedia.org/wiki/Chlorcyclizine

    Chlorcyclizine (Di-Paralene, Mantadil, Pruresidine, Trihistan) is a first-generation antihistamine of the diphenylmethylpiperazine group marketed in the United States and certain other countries. [ 1 ] [ 2 ] [ 3 ] It is used primarily to treat allergy symptoms such as rhinitis , urticaria , and pruritus , and may also be used as an antiemetic .

  9. Chlorphenamine - Wikipedia

    en.wikipedia.org/wiki/Chlorphenamine

    It is a first-generation antihistamine and works by blocking the histamine H 1 receptor. [2] Common side effects include sleepiness, restlessness, and weakness. Other side effects may include dry mouth and wheeziness. [2] Chlorpheniramine was patented in 1948 and came into medical use in 1949. [3] It is available as a generic medication and ...