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  2. Statin - Wikipedia

    en.wikipedia.org/wiki/Statin

    The most important adverse side effects are muscle problems, an increased risk of diabetes mellitus, and increased liver enzymes in the blood due to liver damage. [ 5 ] [ 65 ] Over 5 years of treatment statins result in 75 cases of diabetes, 7.5 cases of bleeding stroke , and 5 cases of muscle damage per 10,000 people treated. [ 34 ]

  3. Maropitant - Wikipedia

    en.wikipedia.org/wiki/Maropitant

    Maropitant undergoes 1st-pass metabolism by liver enzymes, mainly CYP2D15 (which has high affinity for maropitant and clears over 90% of it) but also by the lower-affinity CYP3A12. [ 11 ] [ 12 ] Repeat dosing of maropitant eventually saturates CYP2D15, causing the drug to accumulate due to reduced clearance. [ 5 ]

  4. Rosuvastatin - Wikipedia

    en.wikipedia.org/wiki/Rosuvastatin

    Common side effects include abdominal pain, nausea, headaches, and muscle pains. [6] Serious side effects may include rhabdomyolysis, liver problems, and diabetes. [6] Use during pregnancy may harm the baby. [6] Like all statins, rosuvastatin works by inhibiting HMG-CoA reductase, an enzyme found in the liver that plays a role in producing ...

  5. Liver shunt in dogs: Vet explains the symptoms, causes, and ...

    www.aol.com/lifestyle/liver-shunt-dogs-vet...

    Shunting the issue - Liver shunts in dogs. This article will discuss what exactly a liver shunt is, how to recognize the signs of a liver shunt, what treatment options are available, and how to ...

  6. Pravastatin - Wikipedia

    en.wikipedia.org/wiki/Pravastatin

    Common side effects include joint pain, diarrhea, nausea, headaches, and muscle pains. [5] Serious side effects may include rhabdomyolysis, liver problems, and diabetes. [5] Use during pregnancy may harm the fetus. [5] Like all statins, pravastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver that plays a role in producing ...

  7. Pitavastatin - Wikipedia

    en.wikipedia.org/wiki/Pitavastatin

    Pitavastatin is a lipophilic statin. [8] [9] Reports indicate that this statin may lead to fewer muscle side effects than other statins. [10] One study found that coenzyme Q 10 was not reduced as much as with certain other statins (though this is unlikely given the inherent chemistry of the HMG-CoA reductase pathway that all statin drugs ...