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Pancreatic polypeptide cells are most active and secrete more pancreatic polypeptide after a meal with high protein, fasting, physical activity, and acute hypoglycemia. These same cells are inhibited by somatostatin, an inhibitory gastrointestinal hormone, and the presence of glucose. [7] Pancreatic Polypeptide From a Mouse Cell
Immunohistochemistry for pancreatic polypeptide in a mouse pancreas, 200×. Pancreatic polypeptide (PP) is a polypeptide secreted by PP cells in the endocrine pancreas.It is a hormone and it regulates pancreatic secretion activities, and also impacts liver glycogen storage and gastrointestinal secretion.
release breast milk Stimulates contraction of cervix and vagina. Involved in orgasm, trust between people, [2] and circadian homeostasis (body temperature, activity level, wakefulness). [3] 50 Pancreatic polypeptide: Peptide: Pancreas: PP cells: pancreatic polypeptide receptor 1: Self-regulation of pancreatic secretions (endocrine and exocrine).
The endocrine cells constitute the beta cells which make insulin, alpha cells which secrete glucagon, delta cells which secrete somatostatin and the PP-cells which secrete pancreatic polypeptide. [3] Pancreatic progenitor cells have been shown to arise from cells originating from the developing foregut during mammalian development.
Enteroendocrine cells are specialized cells of the gastrointestinal tract and pancreas with endocrine function. They produce gastrointestinal hormones or peptides in response to various stimuli and release them into the bloodstream for systemic effect, diffuse them as local messengers, or transmit them to the enteric nervous system to activate nervous responses.
Vasoactive intestinal peptide, also known as vasoactive intestinal polypeptide or VIP, is a peptide hormone that is vasoactive in the intestine. VIP is a peptide of 28 amino acid residues that belongs to a glucagon/secretin superfamily, the ligand of class II G protein–coupled receptors. [5]
Delta cells comprise ca 5% of the cells in the islets [1] but may interact with many more islet cells than suggested by their low numbers. In rodents, delta-cells are located in the periphery of the islets; in humans the islet architecture is generally less organized and delta-cells are frequently observed inside the islets as well. [2]
Marine biogenic calcification is the production of calcium carbonate by organisms in the global ocean.. Marine biogenic calcification is the biologically mediated process by which marine organisms produce and deposit calcium carbonate minerals to form skeletal structures or hard tissues.