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Melanonychia is a black or brown pigmentation of a nail, and may be present as a normal finding on many digits in Afro-Caribbeans, as a result of trauma, systemic disease, or medications, or as a postinflammatory event from such localized events as lichen planus or fixed drug eruption.
Melanonychia (longitudinal streaking that darkens or does not grow out), especially on the thumb or big toe, may indicate subungual melanoma. White lines across the nail (leukonychia striata, or transverse leukonychia) may be Mees' lines or Muehrcke's lines. Small white patches are known as leukonychia punctata.
Conditions of the human integumentary system constitute a broad spectrum of diseases, also known as dermatoses, as well as many nonpathologic states (like, in certain circumstances, melanonychia and racquet nails).
A black line in your nail can be a sign of melanoma, or it can be a normal part of your nail bed. A woman's story can help you identify the difference.
A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. [1]
Onychomadesis is defined by the nail plate's detachment from the matrix, its continuous connection to the nail bed, and, frequently but not always, shedding. [4] Beau lines are transverse ridges on the nail plates. [5]
Chromonychia can be induced by antineoplastic drugs with few distinct forms, the most frequently seen is melanonychia. [2] Although a few cytostatics may cause these changes, the drugs most commonly involved are adriamycin, cyclophosphamide and vincristine, or in polychemotherapy [3] [4] Also chromonychia is associated with AIDS.
Muehrcke's lines were described by American physician Robert C. Muehrcke (1921–2003) in 1956. In a study published in BMJ, he examined patients with known chronic hypoalbuminemia and healthy volunteers, finding that the appearance of multiple transverse white lines was a highly specific marker for low serum albumin (no subject with the sign had SA over 2.2 g/dL), was associated with severity ...