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A hormonal intrauterine device (IUD), also known as an intrauterine system (IUS) with progestogen and sold under the brand name Mirena among others, is an intrauterine device that releases a progestogenic hormonal agent such as levonorgestrel into the uterus. [2]
The typical dosage is either 1.5 mg taken once or 0.75 mg taken 12–24 hours apart. [37] The effectiveness in both methods is similar. [ 37 ] The most widely used form of oral emergency contraception is the progestin-only pill , which contains a 1.5 mg dosage of levonorgestrel. [ 36 ]
Mirena [30] Skyla [31] Liletta [32] Kyleena [33] Hormone (total in device) None 52 mg levonorgestrel 13.5 mg levonorgestrel 52 mg levonorgestrel 19.5 mg levonorgestrel Initial amount released None 20 μg/day 14 μg/day 18.6 μg/day 16 μg/day Approved effectiveness 10 years (12 years) 5 years (10 years) 3 years 3 years (5 years) 5 years
Here’s what to keep in mind about type 2 diabetes medications used to support weight loss and weight loss injections: Weight loss injections are safe and effective when used as prescribed .
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Desogestrel has a very short terminal half-life of about 1.5 hours while etonogestrel has a relatively long elimination half-life of about 21 to 38 hours, reflecting the nature of desogestrel as a prodrug. [13] [1] [15] Desogestrel and etonogestrel are eliminated exclusively as metabolites 50% in urine and 35% in feces. [13] [11]
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