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Discolysis, also called chemonucleolysis or nucleolysis, is a treatment for a herniated disc that seeks to alleviate associated neurological symptoms through enzymatic or chemical destruction or softening of the nucleus pulposis. [1] The procedure was first reported by Lyman W. Smith in 1964, and used chymopapain.
The second disc replacement to achieve wide clinical use was the prodisc total disc replacement; it continues to have worldwide use today. Designed by French orthopedic spine surgeon Thiery Marnay, M.D., in the late 1980s, early implantations of the prodisc device began in 1990, with a 7-11 year follow-up published in 2005.
Disc herniation can occur in any disc in the spine, but the two most common forms are lumbar disc herniation and cervical disc herniation. The former is the most common, causing low back pain (lumbago) and often leg pain as well, in which case it is commonly referred to as sciatica .
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There are many surgical options for the treatment of degenerative disc disease, including anterior [16] and posterior approaches. The most common surgical treatments include: [ 17 ] Microdiscectomy : A minimally invasive surgical procedure in which a portion of a herniated nucleus pulposus is removed by way of a surgical instrument or laser ...
Microdiscectomy (or microdecompression) is a minimally invasive surgical procedure in which a portion of a herniated nucleus pulposus is removed by way of a surgical instrument. [2] The purpose of this procedure is to relieve the pressure and reduce the local inflammatory reaction around a nerve root, caused by the herniated nucleus pulposus.
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