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Δ-10-Tetrahydrocannabinol (Delta-10-THC, Δ 10-THC, alternatively numbered as Δ 2-THC) is a positional isomer of tetrahydrocannabinol, discovered in the 1980s.Two epimers have been reported in the literature, with the 9-methyl group in either the (R) or (S) conformation; of these, the (R) epimer appears to be the more active isomer as well as the double bond in the 10th position instead of ...
Salves and absorption through the skin (transdermal) are increasingly common in medical uses, both of CBD, THC, and other cannabinoids. Each method leads to subtly different psychoactive effects due to the THC and other chemicals being activated, and then consumed through different administration routes.
[64] 11-OH-THC is the first metabolic product in this pathway. Both Delta-9-THC and 11-OH-THC are psychoactive. The metabolism of THC into 11-OH-THC plays a part in the heightened psychoactive effects of edible cannabis. [65] Next, 11-OH-THC is metabolized in the liver into 11-COOH-THC, which is the second metabolic product of THC.
Δ-3-Tetrahydrocannabinol (often abbreviated as delta-3-THC or Δ 3-THC) is a synthetic isomer of tetrahydrocannabinol (THC) developed during the original research in the 1940s to develop synthetic routes to the natural products Δ 8-THC and Δ 9-THC found in the cannabis. [1]
THC and its 11-OH-THC and THC-COOH metabolites can be detected and quantified in blood, urine, hair, oral fluid or sweat using a combination of immunoassay and chromatographic techniques as part of a drug use testing program or in a forensic investigation. [57] [58] [59] There is ongoing research to create devices capable of detecting THC in ...
Despite the CBD and THC having the same molecular weight, multiple analytical methods are able to differentiate them. [11] "on the recovery of both THC (86.7−90.0%) and CBD (92.3−95.6%). The slightly lower recovery of THC can be explained by the fact that THC is less polar than CBD and more likely to remain in the nonpolar sunflower oil." [11]
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Cannabis concentrate, also called marijuana concentrate, marijuana extract, or cannabis extract, is a tetrahydrocannabinol (THC) and/or cannabidiol (CBD) concentrated mass. Cannabis concentrates contain high THC levels that range from 40% to over 90%, [ 1 ] [ 2 ] stronger in THC content than high-grade marijuana, which normally measures around ...