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  2. Peptide bond - Wikipedia

    en.wikipedia.org/wiki/Peptide_bond

    Peptide bond formation via dehydration reaction. When two amino acids form a dipeptide through a peptide bond, [1] it is a type of condensation reaction. [2] In this kind of condensation, two amino acids approach each other, with the non-side chain (C1) carboxylic acid moiety of one coming near the non-side chain (N2) amino moiety of the other.

  3. Arginylglycylaspartic acid - Wikipedia

    en.wikipedia.org/wiki/Arginylglycylaspartic_acid

    [44] [30] For example, the cyclic peptide ACDCRGDCFCG, also known as RGD4C, was shown to be 200-fold more potent than commonly used linear RGD peptides. [30] The structural rigidity of cyclic RGD peptides improves their binding properties and prevents degradation at the highly susceptible aspartic acid residue, thereby increasing their ...

  4. Ribosomally synthesized and post-translationally modified ...

    en.wikipedia.org/wiki/Ribosomally_synthesized...

    This peptide consists of a core peptide segment which is typically preceded (and occasionally followed) by a leader peptide segment and is typically ~20-110 residues long. The leader peptide is usually important for enabling enzymatic processing of the precursor peptide via aiding in recognition of the core peptide by biosynthetic enzymes and ...

  5. Peptide synthesis - Wikipedia

    en.wikipedia.org/wiki/Peptide_synthesis

    In organic chemistry, peptide synthesis is the production of peptides, ... which decomposes into carbon dioxide (CO 2) and the free amine.

  6. Split and pool synthesis - Wikipedia

    en.wikipedia.org/wiki/Split_and_pool_synthesis

    A template library containing at one end one of the BBs and its code followed by two annealing regions for the codes of the BBs of the two reagent libraries. Each of the two reagent libraries contains a coding oligonucleotide linked with cleavable bonds to the reagent (BB) capable of forming a bond with the already linked BB taking advantage of ...

  7. Peptide library - Wikipedia

    en.wikipedia.org/wiki/Peptide_library

    A peptide library is a tool for studying proteins.Peptide libraries typically contain a large number of peptides that have a systematic combination of amino acids.Usually, solid phase synthesis, e.g. resin as a flat surface or beads, is used for peptide library generation.

  8. List of mass spectrometry software - Wikipedia

    en.wikipedia.org/wiki/List_of_mass_spectrometry...

    BACIQ is a mathematically rigorous approach that integrates peptide intensities and peptide-measurement agreement into confidence intervals for protein ratios. Byos Proprietary: Byos commercial software allows XIC of peptide level mass spec data from any MS vendor and relative quantity of PTM vs unmodified.

  9. Bergmann azlactone peptide synthesis - Wikipedia

    en.wikipedia.org/wiki/Bergmann_azlactone_peptide...

    The Bergmann azlactone peptide synthesis is a classic organic synthesis process for the preparation of dipeptides. In the presence of a base, peptides are formed by aminolysis of N-carboxyanhydrides of amino acids with amino acid esters ( 1 ).