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  2. Guedel's classification - Wikipedia

    en.wikipedia.org/wiki/Guedel's_classification

    Since 1982, ether is not used in the United States. [7] Now, because of the use of intravenous induction agents with muscle relaxants and the discontinuation of ether, elements of Guedel's classification have been superseded by depth of anaesthesia monitoring devices such as the BIS monitor; [5] however, the use of BIS monitoring remains ...

  3. Desflurane - Wikipedia

    en.wikipedia.org/wiki/Desflurane

    Desflurane (1,2,2,2-tetrafluoroethyl difluoromethyl ether) is a highly fluorinated methyl ethyl ether used for maintenance of general anesthesia. Like halothane , enflurane , and isoflurane , it is a racemic mixture of ( R ) and ( S ) optical isomers ( enantiomers ).

  4. History of general anesthesia - Wikipedia

    en.wikipedia.org/wiki/History_of_general_anesthesia

    On 30 March 1842, he administered diethyl ether by inhalation to a man named James Venable, in order to remove a tumor from the man's neck. [102] Long later removed a second tumor from Venable, again under ether anesthesia. He went on to employ ether as a general anesthetic for limb amputations and childbirth. Long, however, did not publish his ...

  5. Inhalational anesthetic - Wikipedia

    en.wikipedia.org/wiki/Inhalational_anesthetic

    Subsequently, about 40 years later, in 1581, Giambattista Delia Porta demonstrated the use of ether on humans although it was not employed for any type of surgical anesthesia. [ 14 ] In modern medicine, Dr. Horace Wells used nitrous oxide for his own dental extraction in 1844.

  6. Enflurane - Wikipedia

    en.wikipedia.org/wiki/Enflurane

    Enflurane (2-chloro-1,1,2-trifluoroethyl difluoromethyl ether) is a halogenated ether. Developed by Ross Terrell in 1963, it was first used clinically in 1966. It was increasingly used for inhalational anesthesia during the 1970s and 1980s [2] but is no longer in common use. [3] Enflurane is a structural isomer of isoflurane. It vaporizes ...

  7. Halogenated ether - Wikipedia

    en.wikipedia.org/wiki/Halogenated_ether

    Inhaled agents like diethyl ether are critical in anesthesia. Diethyl ether initially replaced non-flammable (but more toxic) halogenated hydrocarbons like chloroform and trichloroethylene. Halothane is a halogenated hydrocarbon anesthetic agent that was introduced into clinical practice in 1956. Due to its ease of use and improved safety ...

  8. Merck to buy eye-focused drug developer EyeBio for as ... - AOL

    www.aol.com/news/merck-acquire-eye-drug-company...

    (Reuters) -Merck on Wednesday agreed to buy privately held biotech EyeBio for as much as $3 billion, as it looks to diversify its portfolio of experimental drugs with treatments for eye diseases.

  9. Sevoflurane - Wikipedia

    en.wikipedia.org/wiki/Sevoflurane

    Sevoflurane, sold under the brand name Sevorane, among others, is a sweet-smelling, nonflammable, highly fluorinated methyl isopropyl ether used as an inhalational anaesthetic for induction and maintenance of general anesthesia. After desflurane, it is the volatile anesthetic with the fastest onset. [8]