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Clarke has a trephine in his right hand. The painting is in Harvard Medical School. [1] A trephine (/ t r ɪ ˈ f aɪ n /; from Greek τρύπανον, trypanon 'instrument for boring') [2] is a surgical instrument with a cylindrical blade. It can be of one of several dimensions and designs depending on what it is meant to be used for.
Detail from The Extraction of the Stone of Madness, a painting by Hieronymus Bosch depicting trepanation (c. 1488–1516). Trepanning, also known as trepanation, trephination, trephining or making a burr hole (the verb trepan derives from Old French from Medieval Latin trepanum from Greek trúpanon, literally "borer, auger"), [1] [2] is a surgical intervention in which a hole is drilled or ...
The Jamshidi needle is a trephine needle for performing bone marrow biopsy, whereby a cylindrical sample of tissue, a core biopsy specimen, is obtained. It is a cylindrical needle with a tapered cutting tip. [1] The tapered end reduces the potential of crush artifact. [2]
A 4–5mm diameter hole is drilled into the anterior table of the sinus. The best location of the trephine is the floor of sinus or through the brow ridge. If there is possibility of development of osteomyelitis, the trephine is made inferiorly. Precaution is taken not to injure the supraorbital nerve.
Bone marrow samples can be obtained by aspiration and trephine biopsy. Sometimes, a bone marrow examination will include both an aspirate and a biopsy. The aspirate yields semi-liquid bone marrow, which can be examined by a pathologist under a light microscope and analyzed by flow cytometry , chromosome analysis , or polymerase chain reaction ...
Conomor is said to have married Tryphine, the daughter of his ally Waroch I, but seems later to have violently abused and then murdered her. [3] [4] [5] Conomor was later killed in battle with a rival, and became a legendary villain in Breton history.
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