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Uveitis is estimated to be responsible for approximately 10%-20% of the blindness in the United States. [ 36 ] For non-infectious uveitis, women are more likely (57%) to be affected than men, possibly due to their higher prevalence of related autoimmune diseases . [ 37 ]
The disease may progress to severe inflammation of the uveal layer of the eye (uveitis) with pain and sensitivity of the eyes to light. The affected eye often remains relatively painless while the inflammatory disease spreads through the uvea , where characteristic focal infiltrates in the choroid named Dalén–Fuchs nodules can be seen.
If there is an underlying cause, treatment should be given based on the disease. Non specific treatment measures include cycloplegics , corticosteroids and immunosuppressive drugs . [ 2 ] The biologic drugs that are currently used in treatment of panuveitis include anti tumor necrosis factor , cytokine receptor antibodies and interferon-α .
That is, uveitis refers to a complex category of ocular diseases that can cause blindness if either left untreated or improperly diagnosed. [71] The current challenge of accurately diagnosing uveitis is that often the cause of a specific ocular inflammation is either unknown or multi-layered. [70]
As such, intermediate uveitis may be the first expression of a systemic condition. Infectious causes of intermediate uveitis include Epstein–Barr virus infection, Lyme disease, HTLV-1 virus infection, cat scratch disease, and hepatitis C. Permanent loss of vision is most commonly seen in patients with chronic cystoid macular edema (CME ...
Researchers then analyzed the rate of patients diagnosed with NAION, a rare condition that is the second-leading cause of optic nerve blindness. NAION is believed to be caused by reduced blood ...
Another vision problem, diabetic retinopathy, is the leading cause of blindness in adults and is caused by damage to the retina from high blood sugar levels. What’s more, risk factors for NAION ...
Chorioretinitis is an inflammation of the choroid (thin pigmented vascular coat of the eye) and retina of the eye. It is a form of posterior uveitis.Inflammation of these layers can lead to vision-threatening complications.