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Candida albicans is an opportunistic pathogenic yeast [5] that is a common member of the human gut flora. It can also survive outside the human body. It can also survive outside the human body. [ 6 ] [ 7 ] It is detected in the gastrointestinal tract and mouth in 40–60% of healthy adults.
Candida is located on most mucosal surfaces and mainly the gastrointestinal tract, along with the skin. [3] Candida albicans is one of the most commonly isolated species and can cause infections (candidiasis or thrush) in humans and other animals. In winemaking, some species of Candida can potentially spoil wines. [4]
Candidiasis is a fungal infection due to any species of the genus Candida (a yeast). [4] When it affects the mouth, in some countries it is commonly called thrush. [3] Signs and symptoms include white patches on the tongue or other areas of the mouth and throat. [3]
While Candida albicans is the most common yeast species associated with vaginal thrush, infection by other types of yeast can produce similar symptoms. A Hungarian study of 370 patients with confirmed vaginal yeast infections identified the following types of infection: [18] Candida albicans: 85.7%; Non-albicans Candida (8 species): 13.2%
The yeast Candida albicans can live in people without producing symptoms, and is able to cause both superficial mild candidiasis in healthy people, such as oral thrush or vaginal yeast infection, and severe systemic candidiasis in those who cannot fight infection themselves. [3]
Candida albicans is the most commonly implicated organism in this condition. C. albicans is carried in the mouths of about 50% of the world's population as a normal component of the oral microbiota. [3] This candidal carriage state is not considered a disease, but when Candida species become pathogenic and invade host tissues, oral candidiasis ...
A photomicrograph of Candida albicans showing hyphal outgrowth and other morphological characteristics.. Mannan (oligomannan) is a component of the yeast cell wall.Antibodies to yeast mannans are found at increased frequency in Crohn's disease and ASCA positive Crohn's tend to have lower low levels of mannan-binding lectin. [15]
Gram stain of Candida albicans from a vaginal swab, showing hyphae, and chlamydospores, which are 2–4 μm in diameter. A chlamydospore is the thick-walled large resting spore of several kinds of fungi, including Ascomycota such as Candida, [1] Basidiomycota such as Panus, [2] and various Mortierellales species. [3]