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  2. Naldemedine - Wikipedia

    en.wikipedia.org/wiki/Naldemedine

    Naldemedine, sold under the brand name Symproic in the US and Rizmoic in the European Union, is a medication that is used for the treatment of opioid-induced constipation in adults who have previously been treated with a laxative in the European Union, or to treat opioid induced constipation in adults with chronic non-cancer pain in the US.

  3. Naloxegol - Wikipedia

    en.wikipedia.org/wiki/Naloxegol

    Naloxegol (INN; PEGylated naloxol; [4] trade names Movantik and Moventig) is a peripherally acting μ-opioid receptor antagonist developed by AstraZeneca, licensed from Nektar Therapeutics, for the treatment of opioid-induced constipation. [5] It was approved in 2014 in adult patients with chronic, non-cancer pain. [6]

  4. Magnesium Supplements Can Help With Constipation, But Make ...

    www.aol.com/lifestyle/magnesium-supplements-help...

    Magnesium for constipation is a doctor-approved treatment. Experts recommend magnesium citrate or magnesium oxide, and say the oral route is most effective. Magnesium Supplements Can Help With ...

  5. Should You Be Taking a Fiber Supplement If You Can't Poop ...

    www.aol.com/lifestyle/taking-fiber-supplement...

    Just keep in mind that fiber supplements aren’t a magic bullet for constipation relief. It’s also important to eat lots of nutritious high-fiber foods, stay hydrated, be active and manage stress.

  6. Peripherally acting μ-opioid receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Peripherally_acting_μ...

    It acts as an antagonist for MOR, KOR and DOR, but with higher affinity for MOR and KOR than for DOR. Like other PAMORAs, the main goal is the treatment of OIC. [34] Axelopran is also being investigated in fixed-dose combination (FDC) with oxycodone. It is done by using spray coating technology to create an FDC of axelopran and controlled ...

  7. 7. Move more. You may notice that if you take a break from your exercise routine, you get more backed up. “A more sedentary state leads to more constipation,” says Dr. Mathur, who adds that ...

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