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  2. History of syphilis - Wikipedia

    en.wikipedia.org/wiki/History_of_syphilis

    With the mass production of penicillin from 1943, syphilis could be cured. Syphilis screening was introduced for every pregnancy. Contact tracing was also introduced. [87] By 1956, congenital syphilis had been almost eliminated, and female cases of acquired syphilis had been reduced to a hundredth of their level just 10 years previously. [88]

  3. Jarisch–Herxheimer reaction - Wikipedia

    en.wikipedia.org/wiki/Jarisch–Herxheimer_reaction

    A Jarisch–Herxheimer reaction is a sudden and typically transient reaction that may occur within 24 hours of being administered antibiotics for an infection by a spirochete, including syphilis, leptospirosis, Lyme disease, and relapsing fever. [1]

  4. Syphilis - Wikipedia

    en.wikipedia.org/wiki/Syphilis

    Syphilis can be effectively treated with antibiotics. [4] The preferred antibiotic for most cases is benzathine benzylpenicillin injected into a muscle. [4] In those who have a severe penicillin allergy, doxycycline or tetracycline may be used. [4] In those with neurosyphilis, intravenous benzylpenicillin or ceftriaxone is recommended. [4]

  5. Congenital syphilis - Wikipedia

    en.wikipedia.org/wiki/Congenital_syphilis

    Congenital syphilis is syphilis that occurs when a mother with untreated syphilis passes the infection to her baby during pregnancy or at birth. [4] It may present in the fetus, infant, or later. [1] [5] Clinical features vary and differ between early onset, that is presentation before 2-years of age, and late onset, presentation after age 2 ...

  6. List of syphilis cases - Wikipedia

    en.wikipedia.org/wiki/List_of_syphilis_cases

    Cause of death disputed, but symptoms match to mercury poisoning from syphilis treatment. [10] Robert Schumann (1810–1856), German composer Acquired syphilis from a prostitute in the age of 21. [11] Bram Stoker (1847–1912), Irish author Cause of death listed as "Locomotor ataxia 6 months", presumed to be a reference to syphilis. [12] [13]

  7. Tuskegee Syphilis Study - Wikipedia

    en.wikipedia.org/wiki/Tuskegee_Syphilis_Study

    The Tuskegee Study of Untreated Syphilis in the Negro Male [1] (informally referred to as the Tuskegee Experiment or Tuskegee Syphilis Study) was a study conducted between 1932 and 1972 by the United States Public Health Service (PHS) and the Centers for Disease Control and Prevention (CDC) on a group of nearly 400 African American men with syphilis.

  8. Treponema pallidum - Wikipedia

    en.wikipedia.org/wiki/Treponema_pallidum

    Many of the syphilis treatment therapies only lead to bacteriostatic results, unless larger concentrations of penicillin are used for bactericidal effects. [ 65 ] [ 66 ] Penicillin overall is the most recommended antibiotic by the Centers for Disease Control, as it shows the best results with prolonged use.

  9. John Friend Mahoney - Wikipedia

    en.wikipedia.org/wiki/John_Friend_Mahoney

    Mahoney confirmed this and also began to test penicillin for syphilis treatment, first in vitro without success, then in rabbits. He led the Terre Haute Prison experiments and supervised Dr. John C. Cutler in the Guatemala Syphilis Experiment. By 1929, Dr. Mahoney worked as the director of the Venereal Disease Research Lab in Staten Island ...