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The Jackson Laboratory (often abbreviated as JAX) is an independent, non-profit biomedical research institution which was founded by Clarence Cook Little in 1929. [2] It employs over 3,000 employees in Bar Harbor, Maine; Sacramento, California; Farmington, Connecticut; Shanghai, China; and Yokohama, Japan. [3]
Mouse Genome Informatics (MGI) is a free, online database and bioinformatics resource hosted by The Jackson Laboratory, with funding by the National Human Genome Research Institute (NHGRI), the National Cancer Institute (NCI), and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). [1]
The Jackson Laboratory in Bar Harbor, Maine is currently one of the world's largest suppliers of laboratory mice, at around 3 million mice a year. [5] The laboratory is also the world's source for more than 8,000 strains of genetically defined mice and is home of the Mouse Genome Informatics database. [6]
The NSG mouse (NOD scid gamma mouse) is a brand of immunodeficient laboratory mice, developed and marketed by Jackson Laboratory, which carries the strain NOD.Cg-Prkdc scid Il2rg tm1Wjl /SzJ. NSG branded mice are among the most immunodeficient described to date. [1] NSG branded mice lack mature T cells, B cells, and natural killer (NK) cells. [2]
It is the most widely used "genetic background" for genetically modified mice for use as models of human disease. They are the most widely used and best-selling mouse strain due to the availability of congenic strains, easy breeding, and robustness. [1] The median lifespan of C57BL/6 mice is 27–29 months and the maximum lifespan is about 36 ...
[2] [4] In 1967, he was promoted to the position of senior staff scientist at The Jackson Lab, a position now designated as professor. [2] Stevens spent his entire professional career at The Jackson Laboratory, except a sabbatical year from 1961 to 1962 which he spent as a Guggenheim Fellow at the Laboratoire d’Embryologie Nogent sur Marne.
The Jackson Laboratory was (and still is) the world's mecca for mouse genetics. From 1933 to 1934, Snell was a teacher at Washington University in St. Louis . After brief stints as teachers, in 1935 Snell joined the staff of The Jackson Laboratory in Bar Harbor on Mount Desert Island on the coast of Maine and he remained there for the entire ...
The first ob/ob mouse arose by chance in a colony at the Jackson Laboratory in 1949. [1] The mutation is recessive. Mutant mice are phenotypically indistinguishable from their unaffected littermates at birth, but gain weight rapidly throughout their lives, reaching a weight three times that of unaffected mice.