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  2. Patient derived xenograft - Wikipedia

    en.wikipedia.org/wiki/Patient_derived_xenograft

    Cancer cell lines are originally derived from patient tumors, but acquire the ability to proliferate within in vitro cell cultures. As a result of in vitro manipulation, cell lines that have been traditionally used in cancer research undergo genetic transformations that are not restored when cells are allowed to grow in vivo. [9]

  3. Predictive modelling - Wikipedia

    en.wikipedia.org/wiki/Predictive_modelling

    The first clinical prediction model reporting guidelines were published in 2015 (Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD)), and have since been updated. [10] Predictive modelling has been used to estimate surgery duration.

  4. Warburg hypothesis - Wikipedia

    en.wikipedia.org/wiki/Warburg_hypothesis

    Scientist Otto Warburg, whose research activities led to the formulation of the Warburg hypothesis for explaining the root cause of cancer.. The Warburg hypothesis (/ ˈ v ɑːr b ʊər ɡ /), sometimes known as the Warburg theory of cancer, postulates that the driver of carcinogenesis (cancer formation) is insufficient cellular respiration caused by insult (damage) to mitochondria. [1]

  5. List of databases for oncogenomic research - Wikipedia

    en.wikipedia.org/wiki/List_of_databases_for_onco...

    Databases for oncogenomic research are biological databases dedicated to cancer data and oncogenomic research. They can be a primary source of cancer data, offer a certain level of analysis (processed data) or even offer online data mining .

  6. Cancer research - Wikipedia

    en.wikipedia.org/wiki/Cancer_research

    Cancer research is research into cancer to identify causes and develop strategies for prevention, diagnosis, treatment, and cure. Cancer research ranges from epidemiology, molecular bioscience to the performance of clinical trials to evaluate and compare applications of the various cancer treatments.

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  8. PICO process - Wikipedia

    en.wikipedia.org/wiki/PICO_process

    It was argued that PICO may be useful for every scientific endeavor even beyond clinical settings. [2] This proposal is based on a more abstract view of the PICO mnemonic, equating them with four components that is inherent to every single research, namely (1) research object; (2) application of a theory or method; (3) alternative theories or methods (or the null hypothesis); and (4) the ...

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