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The linear no-threshold model (LNT) is a dose-response model used in radiation protection to estimate stochastic health effects such as radiation-induced cancer, genetic mutations and teratogenic effects on the human body due to exposure to ionizing radiation. The model assumes a linear relationship between dose and health effects, even for ...
Studies on the effect of radiation on rats and mice started during and immediately following World War II. [3] Although data from these early studies contributed to setting radiation exposure limits for humans, the small size and short life span of rodents made it difficult to confidently extrapolate what low-level exposure to radiation over ...
Joseph G. Hamilton was the primary researcher for the human plutonium experiments done at U.C. San Francisco from 1944 to 1947. [1] Hamilton wrote a memo in 1950 discouraging further human experiments because the AEC would be left open "to considerable criticism," since the experiments as proposed had "a little of the Buchenwald touch."
The cover to the Project 4.1 Final Report, "Study of Response of Human Beings Accidentally Exposed to Significant Fallout Radiation" Project 4.1 was the designation for a medical study and experimentation conducted by the United States of those residents of the Marshall Islands exposed to radioactive fallout from the 1 March 1954 Castle Bravo nuclear test at Bikini Atoll, which had an ...
Human epidemiology data, including uncertainties in statistics limitations of epidemiology data; dosimetry of exposed cohorts; bias, including misclassification of cancer deaths, and; the transfer of risk across populations. The DDREF factor that is used to scale acute radiation exposure data to low-dose and dose-rate radiation exposures.
The most widely accepted model posits that the incidence of cancers due to ionizing radiation increases linearly with effective radiation dose at a rate of 5.5% per sievert. [3] If this linear model is correct, then natural background radiation is the most hazardous source of radiation to general public health, followed by medical imaging as a ...
A 0.05 Gy dose will increase death due to cancer 10 fold, from the normal 0.5 per 1000 birth rate to a rate of 5 per 1,000. [ citation needed ] An antenatal dose of 1 Gy in the first trimester causes the lifetime risk of fatal cancer sometime in the child's life to increase from c. 25% in non-exposed humans to 100% in the first trimester after ...
The notion of radiation hormesis has been rejected by the National Research Council's (part of the National Academy of Sciences) 16-year-long study on the Biological Effects of Ionizing Radiation. "The scientific research base shows that there is no threshold of exposure below which low levels of ionizing radiation can be demonstrated to be ...