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Side effects of nandrolone decanoate may include symptoms of masculinization like acne, increased hair growth, and voice changes. [3] The medication is a synthetic androgen and anabolic steroid and hence is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT).
[8] [15] Nandrolone has strong anabolic effects and weak androgenic effects, which give them a mild side effect profile and make them especially suitable for use in women and children. [8] [15] [16] There are metabolites of Nandrolone that act as long-lasting prodrugs in the body, [8] such as 5α-Dihydronandrolone.
It is a major metabolite of nandrolone and is formed from it by the actions of the enzyme 5α-reductase analogously to the formation of dihydrotestosterone (DHT) from testosterone. [ 1 ] [ 2 ] When testosterone is 5α-reduced into DHT, which is a much more potent AAS in comparison, its effects are potentiated on a local level.
[18] [19] Nandrolone decanoate is approved for this use. [20] Although they have been indicated for this indication, AAS saw very little use for this purpose due to their virilizing side effects. [18] [21] Aiding weight gain following surgery or physical trauma, during chronic infection, or in the context of unexplained weight loss. [22] [23]
It was the first nandrolone ester to be introduced, followed by nandrolone decanoate in 1962, and has been one of the most widely used nandrolone esters. [3] [14] However, in more recent times, the drug has been largely superseded by nandrolone decanoate, which is longer-acting and more convenient to use.
Dimethyltrienolone is an extremely potent agonist of the androgen and progesterone receptors and hence AAS and progestogen. [1] In animal bioassays, it was shown to possess more than 100 times the anabolic and androgenic potency of the reference AAS methyltestosterone. [1]
RSV vaccine side effects in older adults . The CDC lists the following as possible side effects of the RSV vaccine: Pain, redness, and swelling where the shot is given. Fatigue. Fever. Headache ...
Nandrolone acetate, also known as 19-nortestosterone 17β-acetate or as estr-4-en-17β-ol-3-one 17β-acetate, is a synthetic, injected anabolic–androgenic steroid (AAS) and a derivative of 19-nortestosterone (nandrolone) that was never marketed. [1] [2] [3] It is an androgen ester – specifically, the C17β acetate ester of nandrolone. [1] [2