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Pyrantel is a medication used to treat a number of parasitic worm infections. [2] This includes ascariasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis, and trichinellosis. [2] It is taken by mouth. [2] Side effects include nausea, headache, dizziness, trouble sleeping, and rash. [2]
Pyrantel pamoate (also called pyrantel embonate, brand names e.g., Reese's Pinworm Medicine, Pin-X, Combantrin, Anthel, Helmintox, and Helmex) kills adult pinworms through neuromuscular blockade, [27] and is considered as effective as the benzimidazole compounds and is used as a second-line medication. [9] Pyrantel pamoate is available over the ...
The pinworm (genus Enterobius) is a type of roundworm (nematode), and three species of pinworm have been identified with certainty. [15] Humans are hosts only to Enterobius vermicularis (formerly Oxyurias vermicularis). [16] Chimpanzees are host to Enterobius anthropopitheci, which is morphologically distinguishable from the human pinworm. [5]
Co., Ltd.) tablet (for human use) Distoside (Chandra Bhagat Pharma Pvt Ltd) tablet (for human use) Droncit (Bayer) for veterinary use; Drontal (combination with pyrantel pamoate) (Bayer) for veterinary use; D-Worm for veterinary use; note that D-Worm also makes roundworm medicine containing piperidine which is not effective against tapeworms.
In the article, it says: "Dosage is 11 mg/kg not to exceed 1 g as a single dose." Does this mean 11mg of pyrantel embonate or 11mg of pure pyrantel? In the package insert of a German pyrantel drug ("Helmex"), it says dosage is 10mg/kg, with one tablet containing 720mg of pyrantel embonate equivalent to 250mg of pure pyrantel.
Pyrantel pamoate (for most nematode infections) Thiabendazole ... Resistance to antiparasitics has been a growing concern, especially in veterinary medicine.
Pyrantel pamoate – effective against most parasitic nematodes of the GIT; Macrocyclic lactones are glutamate-gated chloride channel agonists, [8] and include: Avermectins (including ivermectin and moxidectin) - effective against most common intestinal worms, except tapeworms, for which praziquantel is commonly used in conjunction for mass ...
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