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HPV is a group of more than 200 related viruses, which are designated by a number for each virus type. [10] Some HPV types, such as HPV5, may establish infections that persist for the lifetime of the individual without ever manifesting any clinical symptoms. HPV types 1 and 2 can cause common warts in some infected individuals. [18]
HPV+OPC presents in one of four ways: as an asymptomatic abnormality in the mouth found by the patient or a health professional such as a dentist; with local symptoms such as pain or infection at the site of the tumor; with difficulties of speech, swallowing, and/or breathing; or as a swelling in the neck (if the cancer has spread to lymph nodes).
The highest-risk types are HPV 16 and 18; these are responsible for the vast majority of HPV-related cancers, including cancers of the cervix, vagina, vulva, penis, anus, and head and neck.
HPV types 6 and 11 are responsible for causing majority of genital warts whereas HPV types 16, 18, 31, 33, and 35 are also occasionally found. [5] It is spread through direct skin-to-skin contact, usually during oral, manual, vaginal, or anal sex with an infected partner. [4] [8] Diagnosis is generally based on symptoms and can be confirmed by ...
HPV, the human papilloma virus, caused the cancer on base of Moog’s tongue. A lump in the neck due to a swollen lymph node that slowly gets bigger is a common symptom of cancers in the mouth ...
A description of human papillomavirus (HPV) by electron microscopy was given in 1949, and HPV-DNA was identified in 1963. [165] It was not until the 1980s that HPV was identified in cervical cancer tissue. [166] It has since been demonstrated that HPV is implicated in virtually all cervical cancers. [167]