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Sjögren's syndrome (SS) is the third-most common rheumatic autoimmune disorder, behind rheumatoid arthritis and systemic lupus erythematosus. [19] There are no geographical differences in the rates of SS. [97] Sjögren's syndrome has been reported in all areas of the world, although regional rates have not been well studied. [97] [98]
Sjögren–Larsson syndrome is a rare autosomal recessive form of ichthyosis with neurological symptoms. [ 1 ] : 485 [ 2 ] : 564 [ 3 ] It can be identified by a triad of medical disorders. The first is ichthyosis , which is a buildup of skin to form a scale-like covering that causes dry skin and other problems.
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...
Sjögren syndrome is a long-term autoimmune disease that affects the body's moisture-producing glands (lacrimal and salivary), [29] and often seriously affects other organ systems, such as the lungs, kidneys, and nervous system.
20823 Ensembl ENSG00000138385 ENSMUSG00000068882 UniProt P05455 P32067 RefSeq (mRNA) NM_003142 NM_001294145 NM_001110145 NM_009278 NM_001355265 RefSeq (protein) NP_001281074 NP_003133 NP_001103615 NP_033304 NP_001342194 Location (UCSC) Chr 2: 169.79 – 169.81 Mb Chr 2: 69.69 – 69.7 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Sjögren syndrome type B antigen (SS-B) also known ...
Immunofluorescence pattern of SS-A and SS-B antibodies. Produced using serum from a patient on HEp-20-10 cells with a FITC conjugate. Anti-SSA autoantibodies (anti–Sjögren's-syndrome-related antigen A autoantibodies, also called anti-Ro, or similar names including anti-SSA/Ro, anti-Ro/SSA, anti–SS-A/Ro, and anti-Ro/SS-A) are a type of anti-nuclear autoantibodies that are associated with ...
Sjögren syndrome Henrik Samuel Conrad Sjögren ( UK : / ˈ ʃ ɜː ɡ r ɛ n / , US : / ˈ ʃ oʊ ɡ r ɛ n / , [ 1 ] Swedish: [ˈɧø̂ːɡreːn] ; [ 2 ] 23 July 1899, Köping – 17 September 1986, Lund ) [ 3 ] was a Swedish ophthalmologist best known for describing the eponymous condition Sjögren syndrome .
Patients who are seronegative for SSA and SSB antibodies require a mandatory positive lip biopsy result to receive a diagnosis of Sjogren's. One definitive reference for the this comes from Dr. Alan N. Bauer, (2012, The Sjogren's Book, Sjogren's Syndrome Foundation, Wallace, Daniel J. editor; Table 18-1 Diagnostic Testing in Sjogren's, pg. 174.