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The notochord is an elastic, rod-like structure found in chordates. In chordate vertebrates the notochord is an embryonic structure that disintegrates, as the vertebrae develop, to become the nucleus pulposus in the intervertebral discs of the vertebral column.
The notochord plays an integral role in the development of the neural tube. Prior to neurulation, during the migration of epiblastic endoderm cells towards the hypoblastic endoderm, the notochordal process opens into an arch termed the notochordal plate and attaches overlying neuroepithelium of the neural plate. The notochordal plate then ...
The lancelet notochord, unlike the vertebrate spine, extends into the head. This gives the subphylum, Cephalochordata, its name (κεφαλή, kephalē means 'head'). The fine structure of the notochord and the cellular basis of its adult growth are best known for the Bahamas lancelet, Asymmetron lucayanum [51]
The hagfish skeleton comprises the skull, the notochord, and the caudal fin rays. The first diagram of the hagfish endoskeleton was made by Frederick Cole in 1905. [ 43 ] In Cole's monograph, he described sections of the skeleton that he termed "pseudo-cartilage", referring to its distinct properties compared to jawed chordates.
The ventral neural tube is patterned by sonic hedgehog (Shh) from the notochord, which acts as the inducing tissue. Notochord-derived Shh signals to the floor plate, and induces Shh expression in the floor plate. Floor plate-derived Shh subsequently signals to other cells in the neural tube, and is essential for proper specification of ventral ...
From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. The lower half of one sclerotome fuses with the upper half of the adjacent one to form each vertebral body. [11]
Axial mesoderm, or chordamesoderm, is the mesoderm in the embryo that lies along the central axis under the neural tube.. will give rise to notochord; starts as the notochordal process, whose formation finishes at day 20 in humans.
A stiffening rod of tightly packed cells, the notochord, extends the whole length of the body. Unlike vertebrates, the notochord persists in the adult, in the form of a simple dorsal neural tube slightly thickened in the anterior part (the cerebral vesicle). Above it is a nerve cord with a single frontal eye.