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The combination of beta blockers and antihypertensive drugs will work on different mechanism to lower blood pressure. [17] For example, the co-administration of beta-1 blocker atenolol and ACE inhibitor lisinopril could produce a 50% larger reduction in blood pressure than using either drug alone.
Common examples of alpha 1 blockers are Tamsulosin, Prazosin, Phentolamine, and Phenoxybenzamine. [1] Each agent has its own off-label uses, some examples include Tamsulosin for urinary disorders, Prazosin for post-traumatic stress disorder -related nightmares and Raynaud phenomenon , Phentolamine for hypertensive crisis and extravasation of ...
This is a list of adrenergic drugs. These are pharmaceutical drugs , naturally occurring compounds and other chemicals that influence the function of the neurotransmitter epinephrine (adrenaline). Receptor ligands
Alpha blockers, also known as α-blockers or α-adrenoreceptor antagonists, are a class of pharmacological agents that act as antagonists on α-adrenergic receptors (α-adrenoceptors). [ 2 ] Historically, alpha-blockers were used as a tool for pharmacologic research to develop a greater understanding of the autonomic nervous system.
Alpha-1 blockers (also called alpha-adrenergic blocking agents or alpha-1 antagonists) constitute a variety of drugs that block the effect of catecholamines on alpha-1-adrenergic receptors. They are mainly used to treat benign prostatic hyperplasia (BPH), hypertension and post-traumatic stress disorder . [ 1 ]
Adrenergic antagonists reverse the natural cardiovascular effect, based on the type of adrenoreceptor being blocked. For example, if the natural activation of the α 1-adrenergic receptor leads to vasoconstriction, an α 1-adrenergic antagonist will result in vasodilation. [3]
Alpha-2 blockers (or α 2 blockers) are a subset of the alpha blocker class of drugs and are antagonists to the α 2 adrenergic receptor.They are mainly used in research, having found limited clinical application in human medicine.
Sympathomimetic drugs (also known as adrenergic drugs and adrenergic amines) are stimulant compounds which mimic the effects of endogenous agonists of the sympathetic nervous system. Examples of sympathomimetic effects include increases in heart rate , force of cardiac contraction , and blood pressure . [ 1 ]