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Human genetic variants that likely cause dysregulation of critical meiotic processes have been identified in 14 female infertility associated genes. [53] A major cause of female infertility is premature ovarian insufficiency. [54] This insufficiency is a heterogeneous disease that affects about 1% of women who are under the age of 40. [54]
Symptoms depend on whether the cervical canal is partially or completely obstructed and on the patient's menopausal status. Pre-menopausal patients may have a build up of blood inside the uterus which may cause infection, sporadic bleeding, or pelvic pain. Patients also have an increased risk of infertility and endometriosis. [1]
Premenopausal women with hematometra often experience abnormal vaginal bleeding, including dysmenorrhea (pain during menstruation) or amenorrhea (lack of menstruation), while postmenopausal women are more likely to be asymptomatic. [3] Due to the accumulation of blood in the uterus, patients may develop low blood pressure or a vasovagal ...
A woman practicing symptoms-based fertility awareness may choose to observe one sign, two signs, or all three. Many women experience secondary fertility signs that correlate with certain phases of the menstrual cycle, such as abdominal pain and heaviness, back pain, breast tenderness, and mittelschmerz (ovulation pains).
Male infertility is responsible for 20–30% of infertility cases, while 20–35% are due to female infertility, and 25–40% are due to combined problems in both partners. [29] [5] In 10–20% of cases, no cause is found. [5] The most common cause of female infertility are ovulation problems, usually manifested by scanty or absent menstrual ...
Its rupture can create sharp, severe pain on the side of the ovary on which the cyst appears. This sharp pain (sometimes called mittelschmerz) occurs in the middle of the menstrual cycle, during ovulation.
Female genital disease is a disorder of the structure or function of the female reproductive system that has a known cause and a distinctive group of symptoms, signs, or anatomical changes. The female reproductive system consists of the ovaries , fallopian tubes , uterus , vagina , and vulva .
Definitions of cervical weakness vary, but one that is frequently used is the inability of the uterine cervix to retain a pregnancy in the absence of the signs and symptoms of clinical contractions, or labor, or both in the second trimester. [1] Cervical weakness may cause miscarriage or preterm birth during the second and third trimesters.