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2. Hemoglobin electrophoresis - Wikipedia

   en.wikipedia.org/wiki/Hemoglobin_electrophoresis

   Hemoglobin electrophoresis is a blood test that can detect different types of hemoglobin. The test can detect hemoglobin S, the form associated with sickle cell disease, as well as other abnormal types of hemoglobin, such as hemoglobin C. It can also be used to investigate thalassemias, which are disorders caused by defective hemoglobin production.

3. Sickle cell disease - Wikipedia

   en.wikipedia.org/wiki/Sickle_cell_disease

   Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders that are typically inherited. [2] The most common type is known as sickle cell anemia. [2] Sickle cell anemia results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. [2]

4. List of ICD-9 codes 280–289: diseases of the blood and blood ...

   en.wikipedia.org/wiki/List_of_ICD-9_codes_280...

   288.6 Elevated white blood cell count. 288.60 Leukocytosis, unspecified; 288.61 Lymphocytosis (symptomatic) 288.62 Leukemoid reaction; 288.63 Monocytosis (symptomatic) 288.64 Plasmacytosis; 288.65 Basophilia; 288.66 Bandemia; 288.8 Other specified disease of white blood cells; 288.9 Abnormal white blood cells, unspec. 289 Other diseases of ...

5. Sickle cell trait - Wikipedia

   en.wikipedia.org/wiki/Sickle_cell_trait

   Those who are heterozygous for the sickle cell allele produce both normal and abnormal hemoglobin (the two alleles are codominant with respect to the actual concentration of hemoglobin in the circulating cells). Sickle cell disease is a blood disorder wherein there is a single amino acid substitution in the hemoglobin protein of the red blood ...

6. Hemoglobin C - Wikipedia

   en.wikipedia.org/wiki/Hemoglobin_C

   [18] [19] In 1950, Itano and James V. Neel discovered from two African-American families a different blood condition very similar to sickle cell disease. [20] [21] Five of the ten individuals indicated sickled RBCs. But the condition was harmless as the individuals had no anaemia. Thus, it was not clear whether it was involved in sickle cell ...

7. Duffy antigen system - Wikipedia

   en.wikipedia.org/wiki/Duffy_antigen_system

   Duffy antigen-negative individuals with sickle cell anaemia tend to sustain more severe organ damage than do those with the Duffy antigen. [103] Duffy-positive patients exhibit higher counts of white blood cells, polynuclear neutrophils, higher plasma levels of IL-8 and RANTES than Duffy-negative patients. [104]