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Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs. [ 2 ] [ 6 ] [ 8 ] The disease can be either localized to the skin or involve other organs, as well. [ 2 ]
Diabetic retinopathy (also known as diabetic eye disease) is a medical condition in which damage occurs to the retina due to diabetes.It is a leading cause of blindness in developed countries and one of the lead causes of sight loss in the world, even though there are many new therapies and improved treatments for helping people live with diabetes.
The causes of macular edema are numerous and different causes may be inter-related. It is commonly associated with diabetes.Chronic or uncontrolled diabetes type 2 can affect peripheral blood vessels including those of the retina which may leak fluid, blood and occasionally fats into the retina causing it to swell.
Evidence shows that laser therapy is generally safe and improves visual symptoms in sickle cell and diabetic retinopathy. [23] [24] In recent years targeting the pathway controlling vessel growth or angiogenesis has been promising. Vascular endothelial growth factor (VEGF) seems to play a vital role in promoting neovascularization. Using anti ...
Cotton wool spots are typically a sign of another disease state, most common of which is diabetic retinopathy. [2] The irregularly shaped white patches are a result of ischemia , or reduced blood flow and oxygen, in the retinal nerve fiber layer , which is located in the distribution of the capillaries of the superficial layer of the retina. [ 2 ]
Endocrinologists share uncommon symptoms of diabetes that may indicate type 1, type 2, or prediabetes. Some signs include infections and dry skin.
Most patients (over 80%) have vascular symptoms and Raynaud's phenomenon, which leads to attacks of discoloration of the hands and feet in response to cold. Raynaud's normally affects the fingers and toes. Systemic scleroderma and Raynaud's can cause painful ulcers on the fingers or toes, which are known as digital ulcers.
Autoimmune retinopathy: Retina: Various Confirmed [97] Autoimmune uveitis: Uvea: Various Confirmed [98] Cogan syndrome: Inner ear and eye None specific Probable [99] Graves' ophthalmopathy: Eye muscles and connective tissue TSH receptor antibodies Confirmed [100] Intermediate uveitis: Uvea Various Probable [101] Ligneous conjunctivitis: Conjunctiva
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